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Organic Molecular Transformation Lab
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A lab that uses familiar, abundant iron as a catalyst to build molecules in an environmentally friendly way.
AboutAbout the lab
Better synthesis from common resources
The Organic Molecular Transformation Lab (Nakamura Lab) develops efficient and sustainable synthetic reactions under the keyword "advanced utilization of underused chemical resources."
Using metal elements that are abundant in the Earth's crust and found everywhere on the planet as catalysts, the lab synthesizes useful, highly functional molecules through practical synthetic reactions with a low environmental impact.
Key terms
- Cross-coupling
- A reaction that uses a catalyst to join two different molecules at a targeted position
- Nanoparticle
- An extremely small particle a few nanometers (billionths of a meter) in size
- Lignin
- A component of wood that hardens cell walls
ResearchResearch themes
Through the pursuit of organic molecular transformation chemistry and its application to creating products and processes, the lab works toward a better society.
*Illustrative imageIron-catalyzed organic synthesis
The lab developed an iron catalyst with bulky phosphine ligands and achieved precise cross-coupling reactions without palladium or nickel catalysts. Development continues with the aim of controlling reactions even more precisely.
*Illustrative imageSupramolecular catalysts
The lab develops supramolecular catalysts that enable fine molecular control, for example by precisely modifying the surface of metal nanoparticle catalysts.
*Illustrative imageMolecular transformation of forest biomass
The lab focuses on developing environmentally benign chemical reactions that directly synthesize functional substances from renewable forest biomass. It has also found methods to synthesize diketones and imidazoles directly from lignin.
MembersFaculty
- ProfessorMasaharu Nakamura
- Associate ProfessorKatsuhiro Isozaki
- LecturerPINCELLA Francesca
- Assistant ProfessorTakahiro Doba
- Program-Specific Assistant ProfessorYuka Nakagawa
- Program-Specific Assistant ProfessorKeito Mineo
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Iron(III)-chloride-hexahydrate-sample” Benjah-bmm27 / Public domain (cropped)
- Iron-catalyzed organic synthesis: “Cross Coupling Reactions” anica pinongcos / CC0 (cropped)
- Supramolecular catalysts: “Supramolecular photochemistry-2” Еремин Вадим Владимирович? / CC BY-SA 3.0 (cropped)
- Molecular transformation of forest biomass: “LigninStructure” 718 Bot at English Wikipedia / Public domain (cropped)
- Related lab (Fundamental Hydrocarbon Chemistry Lab): “Confocal micrograph of stained HeLa” Dedyseptiadi7 / CC BY-SA 4.0 (cropped)
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