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Materials Analytical Chemistry Lab
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A lab that builds molecular probes to read the workings of life in the language of molecules.
AboutAbout the lab
Solving the mysteries of life with the power of chemistry.
The Materials Analytical Chemistry Lab uses the power of chemistry to create molecules, working to elucidate biological phenomena and develop technologies for diagnosing and treating disease.
Living things are collections of chemical molecules, sustained by the concentrations, locations, interactions, and reactions of those molecules, yet how each individual molecule functions is still not understood.
The lab therefore creates "molecular probes" that investigate and control living systems, aiming to understand and manipulate biological phenomena at the molecular level.
By combining organic chemistry to create molecules, chemical biology to approach life through chemistry, and analytical chemistry to understand life, the lab seeks to produce molecular technologies that no one has seen before.
Key terms
- Molecular probe
- A molecule designed to find specific molecules or cells in a living body, or to change how they function
- Chemical biology
- A field that uses artificial molecules to investigate and manipulate the mechanisms of living things
- Analytical chemistry
- A field of chemistry that studies the methods themselves for determining what a substance contains and how much. In the Materials Analytical Chemistry Lab, it is used as a tool for understanding life
NewsLab news
A doctoral student won an Excellent Poster Award at the 20th Symposium on Bio-Related Chemistry
Lab visits are now open to third-year students in the Creative Chemistry course
Hiroshi Nonaka has joined as Associate Professor and launched a new group
ResearchResearch themes
The lab aims to use the power of chemistry to create molecular probes with excellent functions, and to understand and control biological phenomena at the molecular level. By combining organic chemistry, chemical biology, and analytical chemistry to develop probes, the lab works on methods for analyzing and controlling function in whole living organisms such as humans and mice. Specifically, it analyzes specific proteins that play important roles in the living body, analyzes and functionalizes specific cells in the brain that are suggested to be involved in psychiatric and neurological disorders, and develops molecular technologies that lead to the diagnosis and treatment of cancer.
*Illustrative imageAssembling a fluorescent sensor in the brain
By combining a method for chemically modifying receptors in the brain without genetic manipulation with click chemistry, the lab synthesized a fluorescent sensor on receptors in the brain of a living animal and measured the activity of a specific protease (2025).
*Illustrative imageMeasuring with electricity using nanomaterials
Associate Professor Oyama is interested in electron transfer reactions at the interface between an electrode and a solution. He studies electroanalytical chemistry and its applications, focusing on cases where metal nanomaterials speed up reactions on the electrode surface.
MembersFaculty
The members of the Nonaka Group in the Materials Analytical Chemistry Lab consist of faculty, graduate and undergraduate students, administrative assistants, and technical assistants.
- Associate ProfessorMunetaka Oyama
- Associate ProfessorHiroshi Nonaka
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Moseley Hall Chemistry Lab” Mbrickn / CC BY-SA 4.0 (cropped)
- Assembling a fluorescent sensor in the brain: “PVH neurons of Long-Evans rat marked with retrograde tracer floro-gold” Ga Il Kim / CC BY-SA 4.0 (cropped)
- Measuring with electricity using nanomaterials: “Electrochemistry cell” Tiff592 / CC BY-SA 4.0 (cropped)
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