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Fundamental Aging Science Lab
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A lab that searches for genes linked to age-related diseases through genome analysis.
AboutAbout the lab
Seeking the causes of age-related diseases in the genome
The Fundamental Aging Science Lab is a collaborative program run by the Department of Disease Genomics at the National Center for Geriatrics and Gerontology (NCGG). It uses genome analysis to study genes linked to age-related diseases.
The research takes place outside Nagoya University, at the NCGG in Obu, Aichi Prefecture.
Using specimens donated by patients, the lab examines individual differences in genes. This research aims to lead to methods for predicting and preventing disease and to the search for candidate sources of new drugs.
The lab also contributes to genetic diagnosis, which examines gene sequences, for some forms of familial dementia.
Key terms
- Biobank
- A system that collects and stores specimens donated by patients and makes them available for research
- Next-generation sequencer
- A device that reads the sequence of DNA bases in large quantities at once
- Drug discovery seeds
- Candidates that could become the basis of new drugs. The discovery of genes or proteins involved in a disease provides clues to finding them
ResearchResearch themes
The lab aims to use comprehensive genome analysis to clarify the connections among genes and molecules involved in age-related diseases. Based on the results, it works toward developing evidence-based methods for prediction and prevention and searching for drug discovery seeds.
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MembersFaculty
The members of the Department of Disease Genomics consist of the department head, researchers, and research assistants.
- DirectorKouichi Ozaki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Shotgun sequencing lg” National Human Genome Research Institute / Public domain (cropped)
- Comprehensive analysis of genes involved in age-related diseases: “DNA double helix horizontal” Jerome Walker / Public domain (cropped)
- Related lab (老化代謝科学): “Visit to Yee Hong Centre for Geriatric Care ( )” Rocco Rossi / CC BY 2.0 (cropped)
- Related lab (がんシステム情報学): “Illumina MiSeq” Konrad Förstner / CC BY 2.0 (cropped)
- Related lab (がん分析疫学): “DNA damaged by carcinogenic 2-aminofluorene AF” Brian E. Hingerty, Oak Ridge National Laboratory Suse Broyde, New York University Dinshaw J. Patel, Memorial Sloan Kettering Cancer Center / Public domain (cropped)
- Related lab (神経生化学): “Biochemistry Lab” Baitaal / CC BY-SA 3.0 (cropped)
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