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Molecular Cell Biology Lab (Anatomy I)
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A lab that visualizes cells of the central nervous system in living animals with two-photon microscopy to explore neural circuits.
AboutAbout the lab
Visualizing the homeostasis of neural circuits in vivo
The lab visualizes the function and structure of central nervous system cells in vivo using two-photon microscopy.
It investigates how homeostasis is maintained in the activity of the neural circuits that underlie higher brain functions.
It works to clarify new physiological functions of microglia, the immune cells of the central nervous system.
The lab's website presents it together with the Division of Multicellular Circuit Dynamics, Basic Neuroscience Research Area, National Institute for Physiological Sciences, National Institutes of Natural Sciences.
Key terms
- Two-photon microscope
- A microscope that uses laser light to observe deep inside living tissue
- Microglia
- Immune cells in the central nervous system, such as the brain and spinal cord
- Activity-dependent myelination
- The formation of myelin, a sheath around nerve fibers, in response to neural activity
- Holographic microscope
- A microscope that uses light interference to record and observe three-dimensional information
NewsLab news
View More ↗ResearchResearch themes
By visualizing the function and structure of central nervous system cells in vivo with two-photon microscopy, the lab studies how homeostasis is maintained in the neural circuit activity that underlies higher brain functions. The research page lists clarifying new physiological functions of microglia, activity-dependent myelination, and the development of holographic microscopes.
View More ↗MembersFaculty
The lab's members consist of faculty members, project assistant professors, researchers, graduate students, resident physicians, undergraduate students, technical officers, technicians, technical support staff, administrative assistants, and project specialists.As of 2026
- ProfessorHiroaki Wake
- Associate ProfessorIkuko Takeda
- Assistant ProfessorShota Sugio
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Observing Ocular Tissue under Laser Scanning Microscope ( )” National Eye Institute / CC BY 2.0 (cropped)
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