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Kakeyama Lab
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The lab explores how the brain and mind develop and are maintained through the behavior of mice.
AboutAbout the lab
Understanding humans by understanding the mouse brain
The Kakeyama Lab studies the mechanisms by which the brain and mind develop healthily and are maintained.
It uses methods for analyzing animal behavior in detail and techniques for measuring and manipulating neural activity, and it also conducts studies involving human participants.
The lab has investigated how the effects of chemicals experienced in the womb later appear in learning and sociality after the animals have grown up.
The findings are provided as scientific knowledge toward elucidating the mechanisms of psychiatric and neurological diseases and developing drugs and food products.
Key terms
- Environmental neuroscience
- A field that investigates how chemicals and environmental factors in our surroundings affect the development and function of the brain
- Sociality
- The tendency to recognize peers and behave while interacting with them; it has been found in mice as well
- Cognitive flexibility
- The mental ability to switch away from previous ways of doing things when circumstances change
NewsLab news
A collaborative study in which Prof. Kakeyama's lab participated reported neural activity during decision-making
A collaborative study in which Prof. Kakeyama participated visualized the distribution of nanoplastics in the mouse brain
ResearchResearch themes
The lab combines methods for analyzing animal behavior with techniques for measuring and manipulating neural activity to explore how the brain and mind develop and are maintained. It aims to deliver these findings to society as a foundation for elucidating psychiatric and neurological diseases and developing drugs and foods.
*Illustrative imageChemicals and Brain Development
The lab studies mice that were exposed to chemicals such as dioxin during the fetal stage. In a task where mice move back and forth between set locations in an apparatus, the lab found that they could still learn the locations but had difficulty switching when the correct location changed.
*Illustrative imageMouse Cognition and Social Behavior
In recent years, it has become clear that mice also show social behavior. Through experiments, the lab clarifies how cognition and social behavior manifest, for example that a mouse raised alone takes time to fit in when placed in a group.
MembersFaculty
- ProfessorMasaki Kakeyama
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Section of mouse brain (false color)” Tarzerind / CC BY-SA 4.0 (cropped)
- Chemicals and Brain Development: “Coronal section of a mouse brain” Syed07 / CC BY 4.0 (cropped)
- Mouse Cognition and Social Behavior: “Lab mouse mg 3244” Rama / CC BY-SA 2.0 fr (cropped)
- Related lab (Ogihara Lab): “Snow-cholera-map-1” John Snow / Public domain (cropped)
- Related lab (Kato Lab): “Menthol Crystals close up” Debeo Morium / CC BY-SA 3.0 (cropped)
- Related lab (Tsujiuchi Lab): “Temporary housing for nuclear disaster evacuees - Panoramio 59850097” Duff Figgy / CC BY-SA 3.0 (cropped)
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