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Takeda Lab
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The lab creates materials that serve as scaffolds for cells, linking that work to regenerative medicine.

AboutAbout the lab
A lab for biomaterials and regenerative medicine.
The Takeda Lab studies biomaterials aimed at applications in regenerative medicine.
This field lies where medicine, engineering, chemistry, materials science, and cell biology meet and merge, and each member works on research in a different discipline.
The lab's work covers organic and polymer synthesis, materials fabrication, microfabrication of substrate surfaces, control of cell behavior, and construction of regenerated tissue.
What the lab values most is a spirit of "let's give it a try," and it expects members to think for themselves and take on challenges.
Key terms
- Biomaterial
- A material designed to be used inside the body or in contact with cells
- Cell culture scaffold
- A material or structure that serves as a base for attaching and growing cells
- Electrospinning
- A method of spinning a polymer solution into fine fibers by applying a voltage
NewsLab news
A master's student received the Outstanding Poster Presentation Award at the 32nd Annual Meeting of the Cellulose Society of Japan
A result of collaborative research received a Poster Award at the International Symposium on Biomedical Engineering
A master's student was selected for a Highlight Lecture at the 45th Annual Meeting of the Japanese Society for Biomaterials
ResearchResearch themes
The Takeda Lab's research is divided broadly into five groups. Each group takes its own approach to research on biomaterials aimed at regenerative medicine.
*Illustrative imageNano- and Micropatterning
The lab aims to clarify how cells behave on surfaces microfabricated at the nano- and micrometer scale, and to control that behavior at will. Using semiconductor microfabrication technology, it creates substrate surfaces with fine topography and examines the adhesion, migration, morphology, and gene expression of cells seeded on them.
*Illustrative imageNanofibers
The lab aims to elucidate and control cell behavior on nonwoven fabrics made of fibers with nano- to micrometer diameters, and further to build three-dimensional regenerated tissue using them as scaffolds. Using electrospinning, it has produced fibers with pores, fibers with a bilayer structure, and nonwoven fabrics with aligned fibers.
*Illustrative imageGel Fibers
Using a microfluidic device it developed itself, the lab makes polymer gel fibers with embedded cells. The fibers are several hundred micrometers in diameter and several centimeters or more in length, and structures in which different gels and cells are layered can also be made. The goal is to engineer fibrous tissues such as blood vessels, nerve bundles, and muscle fibers.
*Illustrative imageOrganic and Polymer Synthesis
The lab synthesizes functional molecules that respond to external stimuli, along with new polymer materials that contain them. For example, the molecule spiropyran reversibly changes its structure and polarity when exposed to light. The lab aims to amplify this small change into a change in material properties, creating materials that dynamically control cell adhesion, proliferation, migration, and differentiation.
MembersFaculty
The Takeda Lab's members consist of faculty and master's and undergraduate students.As of 2023
- ProfessorNaoya Takeda
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “3D printed Hydrogel Scaffold” Habannn / CC0 (cropped)
- Nano- and Micropatterning: “Micropillars” Ezrado / CC BY-SA 4.0 (cropped)
- Nanofibers: “Material Non-Woven Fabric” Anh Nhi Đỗ Lê / CC0 (cropped)
- Gel Fibers: “Microfluidic chip for point-of-care medical devices” FMNLab / CC BY 4.0 (cropped)
- Organic and Polymer Synthesis: “Optical photochromic lenses” Albarubescens / CC BY-SA 4.0 (cropped)
- Related lab (Yura Lab): “Myoglobin” AzaToth / Public domain (cropped)
- Related lab (Hosokawa Lab): “Single cell sequencing (MDA) (cropped)” Qianli Ma / Public domain (cropped)
- Related lab (Takeoka Lab): “Lipid Islands on Soap Bubble” KarlGaff / CC BY 4.0 (cropped)
- Related lab (Asahi Lab): “Ibuprofen-crystals-polarized-light-microscopy” Janeklass / CC BY 4.0 (cropped)
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