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Semba Lab
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The lab traces how cancer spreads by studying how genes function.
AboutAbout the lab
Elucidating the mechanisms of carcinogenesis and metastasis.
The Semba Lab studies how cancer arises and how it metastasizes, from the standpoint of gene function.
The main clues are the mechanisms by which cancer cells proliferate and the interactions between cancer cells and the cells surrounding them.
The full picture of cancer is still not completely understood, and there is a need for treatments that extend life while preserving patients' quality of life.
Through this research, the lab aims to develop new anticancer drugs.
Key terms
- Oncogene
- A gene that triggers cancer; when overactive, it causes cells to proliferate without limit
- Signal transduction
- The mechanism by which a stimulus from outside the cell is relayed through molecules inside the cell to the nucleus
- Metastasis
- The process in which cancer cells leave the site where they first formed, move to another organ, and proliferate there
NewsLab news
A doctoral student won the Student Excellent Poster Presentation Award at the 78th Annual Meeting of the Japanese Society for Cell Biology
A doctoral student won an Excellent Poster Award at the Tokyo Women's Medical University–Waseda University Research Exchange Seminar
A doctoral student won the MBSJ Poster Award 2025 at the 48th Annual Meeting of the Molecular Biology Society of Japan
A master's student won a Poster Award at the 29th Annual Meeting of the Japanese Association for Molecular Target Therapy of Cancer
A master's student won the Student Excellent Poster Presentation Award at the 76th Annual Meeting of the Japanese Society for Cell Biology
ResearchResearch themes
The Semba Lab studies the mechanisms by which cancer cells proliferate and the communication between cancer cells and the cells that surround them. From this, the lab aims to elucidate the mechanisms of carcinogenesis and metastasis and to develop new anticancer drugs.
View More ↗MembersFaculty
- ProfessorKentaro Semba
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images.
- Top image: “Histopathology of basal-like breast cancer” Mikael Häggström / CC0 (cropped)
- Related lab (西田研究室): “Macs killing cancer cell” Susan Arnold (photographer) / Public domain (cropped)
- Related lab (朝日研究室): “Ibuprofen-crystals-polarized-light-microscopy” Janeklass / CC BY 4.0 (cropped)
- Related lab (井上研究室): “Erratic Flight of Fireflies” Bernd Thaller / CC BY 2.0 (cropped)
- Related lab (大島研究室): “Mouse Brain Coronal (NIH BioArt )” NIAID Ryan Kissinger / Public domain (cropped)
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