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Inoue Lab
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A lab that reads out the activity of neurons with electricity and light to understand how the brain works.

AboutAbout the lab
Exploring how neurons support brain function
The Inoue Lab studies how neurons support the functions of the brain.
Using cultured neurons, brain slices, and direct observation of animal brains, the lab captures the movement of molecules inside cells with electrophysiology and imaging techniques.
The lab precisely measures intracellular signaling confined to neuronal dendrites, aiming to clarify the molecular basis that underlies synaptic plasticity.
Not only neurons but also the function of glial cells is one of the central themes of research.
Key terms
- Synaptic plasticity
- Changes in how efficiently signals pass at the junctions between neurons, depending on how those junctions are used
- Glial cells
- Cells found around neurons that support their function and also exchange information themselves
- Dendrite
- A branch-like extension from a neuron that receives signals from other cells
NewsLab news
View More ↗ResearchResearch themes
The Inoue Lab investigates how higher-order brain functions are built up by measuring how molecules move and what signals flow inside neurons and glial cells. Research combines electrophysiology and imaging techniques with molecular biology methods.
*Illustrative imageSignals from the cells that support the brain
In the brain, not only neurons but also astrocytes, the cells that support them, send signals. The lab visualizes with light how astrocytes release ATP over a range spanning many synapses, and studies its function.
*Illustrative imageCholesterol and immune cell death
Macrophages, a type of immune cell, eventually die when they take up too much cholesterol. The lab found that a large calcium response inside the cell precedes this, and is exploring the pathway leading to cell death.
MembersFaculty
The members of the Inoue Lab consist of faculty members, visiting researchers, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorInoue Inoue
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Erratic Flight of Fireflies” Bernd Thaller / CC BY 2.0 (cropped)
- Signals from the cells that support the brain: “Astrocyte (NIH BioArt )” NIH NIAID Alexander Stewart / Public domain (cropped)
- Cholesterol and immune cell death: “Signet-ring-cell-like foamy macrophage and normal macrophage” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
- Related lab (朝日研究室): “Ibuprofen-crystals-polarized-light-microscopy” Janeklass / CC BY 4.0 (cropped)
- Related lab (大島研究室): “Mouse Brain Coronal (NIH BioArt )” NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (野崎研究室): “Cannabis sativa plant (4)” Chmee2 / CC BY 3.0 (cropped)
- Related lab (佐藤研究室): “Embryo in flower” AudeNommick / CC BY-SA 4.0 (cropped)
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