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Ichihara Lab
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A lab that investigates how environmental chemicals and nanoparticles affect the nervous system and cause cancer.
AboutAbout the lab
Exploring how environmental chemicals affect the body
The Ichihara Lab studies the mechanisms by which environmental chemicals and nanoparticles cause nervous system disorders and cancer.
It is becoming clear that environmental factors activate immune cells involved in inflammation, such as macrophages and microglia, and that this leads to disease.
Using neural stem cells, genetically modified animals, and techniques for analyzing gene expression and the proteome, the lab investigates cell-cell interactions and the molecular basis of pre-disease states (mibyo).
The lab aims to establish biomarkers that predict disease and to use them to help prevent illness.
Key terms
- Microglia
- A type of immune cell involved in inflammation. It is becoming clear that environmental factors can activate microglia and lead to disease.
- Mibyo (pre-disease state)
- The state before a disease develops. This lab aims to clarify its molecular basis.
- Biomarker
- An indicator used to predict disease. The lab aims to establish biomarkers and use them to help prevent illness.
ResearchResearch themes
The lab investigates the mechanisms by which environmental chemicals and nanoparticles cause central nervous system disorders and cancer. Focusing on immune cells involved in inflammation, it aims to establish biomarkers that predict disease and to contribute to disease prevention.
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MembersFaculty
- ProfessorGaku Ichihara
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Toxicology Research at FDA (NCTR - Biochemical Toxicology Division) ( )” The U.S. Food and Drug Administration / Public domain (cropped)
- Environmental chemicals, nanoparticles, and disease: “Blue Grass Chemical Agent-Destruction Pilot Plant Kentucky Department for Environmental Protection ( )” PEO ACWA / CC BY 2.0 (cropped)
- Related lab (月本研究室): “Radiation therapy for cancer” Jakembradford / CC BY-SA 4.0 (cropped)
- Related lab (藤江研究室): “Blood vessels structure” Vslv / CC BY-SA 4.0 (cropped)
- Related lab (中田研究室): “Captive's medical clinic, Camp 6, Guantanamo” DoD / Public domain (cropped)
- Related lab (佐藤(嗣)研究室): “Antique medicine and chemical bottles in Cedar Key Historical Museum in Cedar Key, Florida, US, on 23 January 2021” MatthewHoobin / CC0 (cropped)
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