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Seki Lab
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The lab uses interfacial spectroscopy to uncover how biomolecules interact with water and ions.
AboutAbout the lab
Seeing and designing molecules at bio-interfaces.
The Seki Lab studies bio-interfaces formed by biomolecules and the electronic material surfaces of biosensors.
By combining interfacial spectroscopy with several microscopy techniques, the lab observes what happens there at the molecular level.
The goal is to understand the complex interplay among biomolecules, water, and ions.
It is a new lab that was launched at Institute of Science Tokyo in October 2025.
Key terms
- Interface
- The boundary where two things with different properties meet, such as water and air, or a solid and a liquid.
- Interfacial spectroscopy
- A method that shines light on an interface and analyzes the light that returns to learn how molecules at the interface are arranged and how they move.
- Biosensor
- A device that uses the action of biomolecules to capture a target substance and convert it into an electrical or optical signal.
NewsLab news
Seki Lab launched at Institute of Science Tokyo
New findings announced on the pathways of iodine release into the atmosphere
Associate Professor Seki received the Hirosaki University Young Researcher Excellent Paper Award
Associate Professor Seki received the NF Foundation R&D Encouragement Award
ResearchResearch themes
Using a wide range of approaches, from organic chemistry to surface science, molecular spectroscopy, and device engineering, the lab investigates the structures of functional molecules on electronic material surfaces and biological membranes. It aims to understand, in molecular terms, the many-body interactions among biomolecules, water, and ions.
*Illustrative imageDeveloping new interfacial microscopic spectroscopy
Using the latest interfacial spectroscopic methods, the lab develops measurement instruments to "see" what molecules do and the environments they are in at surfaces and interfaces, which are confined regions, as well as the detailed structures of the molecules.
*Illustrative imageHighly sensitive biosensors
The lab designs bio-electronic interfaces that capture a target protein and convert it into an electronic signal. It uses methods for designing functional biomolecules from scratch, computational prediction models, and measurement methods under development in the lab.
MembersFaculty
- Associate ProfessorTakakazu SekiPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “NIST Membrane Model ( )” National Institute of Standards and Technology / Public domain (cropped)
- Developing new interfacial microscopic spectroscopy: “Mechanical delay stage in an optical setup 01” Aksy88 / CC BY-SA 4.0 (cropped)
- Highly sensitive biosensors: “Molybdenite (GeoDIL number - 1067)” Nessa Eull / CC0 (cropped)
- Related lab (北口研究室): “Crystal Jelly ("Aequorea Victoria"), Monterey Bay Aquarium, Monterey, California, USA” Jim G from Silicon Valley, CA, USA / CC BY 2.0 (cropped)
- Related lab (五十嵐研究室): “Fluorescent nanodiamonds surrounding living HeLa cells” Autor Skutečný / CC BY-SA 4.0 (cropped)
- Related lab (金原研究室): “Lipid Bilayer” US gov / Public domain (cropped)
- Related lab (小畠・三重研究室): “1RRX pdb group” Christopher King / CC BY 3.0 (cropped)
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