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Clinical Pharmaceutics Lab
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A lab that works with the hospital to find drug therapy suited to each patient.
AboutAbout the lab
Research with the medical front line close at hand.
The Clinical Pharmaceutics Lab works with Chiba University Hospital and conducts research with the clinical setting close at hand.
To help patients use the drug best suited to them safely, the lab looks at drugs through a "chemical lens" and places importance on identifying risks.
The professor believes that pharmacists of the future should contribute to patients' drug therapy on the wards together with physicians and nurses.
The professor holds that personalized medicine can be realized by proposing blood drug concentration measurement and genetic testing.
Key terms
- Drug dosage design
- Deciding the type, amount, and method of administering a drug according to the patient's condition
- Personalized medicine
- Medicine that chooses treatments and drugs to fit each patient's constitution and condition
- Blood drug concentration measurement
- Measuring the concentration of a drug in the blood. It is used to judge whether the dose is appropriate
NewsLab news
Assistant Professor Masayuki Ishikawa won the Postdoctoral Award of the Japanese Society of Pharmaceutical Health Care and Sciences
Professor Itsuko Ishii won the Nagai Memorial International Women Scientist Award of the Academy of Pharmaceutical Science and Technology, Japan
ResearchResearch themes
The lab works with the Department of Pharmacy at Chiba University Hospital on a wide range of research to solve problems arising in clinical practice. It conducts basic and clinical analyses of drug dosage design for critically ill patients in intensive care units and patients with rare diseases, as well as basic research on cholesterol accumulation in macrophages and proliferation of vascular smooth muscle cells, which are involved in the onset and progression of arteriosclerosis.
*Illustrative imageMechanisms of arteriosclerosis
It is becoming clear that foam cell formation through cholesterol accumulation in macrophages and the proliferation of vascular smooth muscle cells are involved in the progression of arteriosclerosis, but the detailed mechanisms remain unclear. The lab studies the physiological functions of these cells and works on developing new therapeutic drugs.
*Illustrative imageIndividualizing and optimizing drug therapy
Individual differences in drug efficacy and side effects involve many factors, including aging, pregnancy, liver, kidney, and heart disease, and genetic polymorphisms. The lab identifies factors that affect blood concentration, efficacy, and side effects, and explores the optimal drug therapy for each patient.
MembersFaculty
The members of the Clinical Pharmaceutics Lab consist of faculty and students in the doctoral, master's, and undergraduate programs.As of 2025
- ProfessorItsuko Ishii
- Associate ProfessorMasashi Uchida
- Assistant ProfessorMasayuki Ishikawa
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Hospital Pharmacy” User:Mattes / Public domain (cropped)
- Mechanisms of arteriosclerosis: “Atherosclerosis, HE 1” Patho / CC BY-SA 3.0 (cropped)
- Individualizing and optimizing drug therapy: “Assistant Pharmacist” M Joko Apriyo Putro / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Pharmacotherapeutics Lab): “New pharmacy for Guy's Hospital - geograph.org.uk - 4259421” Stephen Craven / CC BY-SA 2.0 (cropped)
- Related lab (Biopharmaceutics Lab): “Atenolol tablets (UK)” Whispyhistory / CC BY-SA 4.0 (cropped)
- Related lab (Drug Discovery Physical Properties Lab): “Concerta tablets in Japan” Zohang Yuriy / CC BY-SA 4.0 (cropped)
- Related lab (Pharmacy Practice Lab): “Julie Zinihite at the pharmacy at the National Referal Hospital in Honiara, Solomon Islands 2012. Photo- AusAID ( )” Department of Foreign Affairs and Trade / CC BY 2.0 (cropped)
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