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Clinical Research and Treatment Evaluation Lab
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A clinical trial lab that brings new treatments to society through trials for regulatory approval.
AboutAbout the lab
Keep taking on challenges to make patients' futures better.
Clinical Research and Treatment Evaluation supports clinical trials, including trials for regulatory approval, as the Department of Clinical Trials of Chiba University Hospital.
Clinical trials are the final stage of research before drugs and other products can be widely used in society.
The lab has organized an academic research organization (ARO) that supports investigator-initiated clinical trials conducted by physicians themselves, and it also supports research at other universities and companies.
In 2017, Chiba University Hospital was designated a Core Clinical Research Hospital under the Medical Care Act.
Key terms
- Clinical trial for regulatory approval (chiken)
- A trial that tests efficacy and safety in humans in order to obtain national approval for a new drug or medical device.
- Investigator-initiated clinical trial
- A clinical trial that physicians plan and carry out themselves, rather than at the request of a company.
- ARO
- Academic research organization. An organization set up at universities and similar institutions that supports clinical research as a whole, from planning through quality control.
ResearchResearch themes
The lab works with patients, researchers (physicians), companies, and regulatory authorities to support the conduct of highly reliable clinical trials. Through the WISDOM project, it advances investigator-initiated clinical trials together with researchers.
*Illustrative imageTrial for sialorrhea in schizophrenia
This is one of the investigator-initiated clinical trials the lab supports. It evaluates the efficacy and safety of dextromethorphan in patients with schizophrenia who have clozapine-induced sialorrhea. The clinical trial notification was submitted in January 2026.
*Illustrative imageCyclosporine for Kawasaki disease
This is one of the investigator-initiated clinical trials the lab supports. It evaluates the efficacy and safety of cyclosporine in patients diagnosed with Kawasaki disease who carry a mutation in the ITPKC gene. The clinical trial notification was submitted in May 2026.
*Illustrative imageTrial for interstitial pneumonia in dermatomyositis
This is one of the investigator-initiated clinical trials the lab supports. It evaluates the safety and efficacy of a treatment that adds tofacitinib to triple combination therapy in patients with newly diagnosed anti-MDA5 antibody-positive dermatomyositis complicated by interstitial pneumonia.
*Illustrative imageTreatment after carbon-ion radiotherapy for hepatocellular carcinoma
This is one of the investigator-initiated clinical trials the lab supports. It evaluates the safety and efficacy of combination therapy with atezolizumab and bevacizumab as adjuvant therapy after carbon-ion radiotherapy for hepatocellular carcinoma.
MembersFaculty
The members of Clinical Research and Treatment Evaluation consist of faculty and the staff of each office, including the Planning and Coordination Office, Monitoring Office, Biostatistics Office, and Data Management Office.
- ProfessorHideki Hanaoka
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Chiba University Hospital” Waka77 / Public domain (cropped)
- Trial for sialorrhea in schizophrenia: “Pills and medicines 02” BuhaM / CC BY-SA 4.0 (cropped)
- Cyclosporine for Kawasaki disease: “A hospital ward in Assam in response to the 2020 COVID-19 pandemic” AnjanBorah / CC BY-SA 4.0 (cropped)
- Trial for interstitial pneumonia in dermatomyositis: “Hospital Radiology Room Philips DigitalDiagnost Digital Radiography System” Ptrump16 / CC BY-SA 4.0 (cropped)
- Treatment after carbon-ion radiotherapy for hepatocellular carcinoma: “Later stage of the CLARA Accelerator, Daresbury Laboratory” Mystery Ray / CC0 (cropped)
- Related lab (Medical Quality and Safety Lab): “Corridor on the second level - NÄL hospital 3” W.carter / CC0 (cropped)
- Related lab (Japanese Oriental (Kampo) Medicine Lab): “Chinese Medicine” Dr. Bret Mosher / CC BY-SA 4.0 (cropped)
- Related lab (Psychiatry Lab): “Mental Health clinic adapts to 52nd FW needs during COVID- )” U.S. Air Force photo by Senior Airman Kyle Cope / Public domain (cropped)
- Related lab (Neurology Lab): “A Cortical Neuron In Isolation” Dchordpdx / CC BY 4.0 (cropped)
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