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Neurology Lab
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The lab works to overcome intractable neurological diseases through both electrophysiology and clinical practice.
AboutAbout the lab
Overcoming intractable neurological diseases.
The lab's philosophy is to strive to train medical professionals who truly contribute to the advancement of clinical neurology, and to provide the best possible medical care, for the sake of patients.
Aiming to overcome intractable neurological diseases, the lab conducts research in nine research groups, covering conditions from Parkinson's disease to neuroimmunological diseases and dementia.
Using methods such as axonal excitability testing and transcranial magnetic stimulation, the lab investigates how nerve excitability is involved in disease.
Founded in 1978 as the neurology research division of the Brain Function Research Facility, the lab has advanced clinical care and research on neurodegenerative and immune-mediated neurological diseases.
Key terms
- Axon
- The long extension of a nerve cell that carries electrical signals
- Transcranial magnetic stimulation (TMS) testing
- A test that stimulates the brain with magnetic pulses from outside the head to examine how well nerve signals are conducted
- Peripheral nerve
- A nerve that extends from the brain and spinal cord to the limbs and internal organs
NewsLab news
View More ↗ResearchResearch themes
The lab conducts research in nine groups with the aim of overcoming intractable neurological diseases. Using electrophysiological methods, it explores how nerve excitability contributes to neurological disease.
*Illustrative imageParkinson's Disease and Movement Disorders
Through both clinical and basic research, the lab aims to elucidate the pathophysiology of Parkinson's disease and related disorders and to establish treatments. It also studies non-motor symptoms such as autonomic dysfunction and cognitive impairment, and investigates the mechanisms of action and safety of deep brain stimulation.
*Illustrative imageNeuroimmunological Diseases
The lab investigates the pathophysiology of Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy, mainly through electrophysiological approaches. It also conducts clinical and epidemiological studies of multiple sclerosis and neuromyelitis optica.
*Illustrative imageMotor Neuron Diseases
Focusing on amyotrophic lateral sclerosis (ALS), the lab studies the pathophysiology of the disease with attention to the excessive excitability of motor neurons. Based on findings from axonal excitability testing and transcranial magnetic stimulation, it conducts clinical trials, and it also carries out natural history studies that examine the course of the disease without intervention.
*Illustrative imagePeripheral Nerve Diseases
Aiming to develop new diagnostic methods and treatments for peripheral nerve diseases, the lab studies their pathophysiology using neurophysiological methods. It is working on axonal ion channel function testing and on new diagnostic methods based on ultrasound examination of nerves and muscles.
MembersFaculty
The lab's members consist of faculty, staff physicians, graduate students, and residents in specialty training. Faculty from other departments within the university, such as Medical Education and the Division of Clinical Genetics, also take part in supervision.
- ProfessorHitoshi Shimada
- Associate ProfessorMasahiro Mori
- Clinical Associate ProfessorShigeki Hirano
- Clinical LecturerAkiyuki Uzawa
- Clinical LecturerKazumoto Shibuya
- Clinical LecturerAtsuhiko Sugiyama
- Clinical LecturerHiroki Masuda
- Assistant ProfessorTomoki Suichi
- Project Assistant ProfessorYoshikazu Nakano
- Project Assistant ProfessorManato Yasuda
- Project Assistant ProfessorEtsuko Nokoya
- Project ProfessorSatoshi Kuwabara
- ProfessorShoichi Ito
- Project ProfessorYoshitaka Yamanaka
- Project Associate ProfessorSetsu Sawai
- Project LecturerNobuyuki Araki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “A Cortical Neuron In Isolation” Dchordpdx / CC BY 4.0 (cropped)
- Parkinson's Disease and Movement Disorders: “Deep brain stimulation in a Parkinson's Disease patient” Andreashorn / CC BY-SA 4.0 (cropped)
- Neuroimmunological Diseases: “Axial MRI scans of a person with multiple sclerosis ( )” NIH Image Gallery from Bethesda, Maryland, USA / Public domain (cropped)
- Motor Neuron Diseases: “Neuro-ms” Baburov / CC BY-SA 4.0 (cropped)
- Peripheral Nerve Diseases: “EMG - SIMI” D. Gordon E. Robertson / CC BY-SA 3.0 (cropped)
- Related lab (脳神経外科学): “Эндоскоп (ФЦН Тюмень)” Дмитрий Кошелев / CC BY-SA 3.0 (cropped)
- Related lab (循環器内科学): “A cardiac catheterization procedure in the Naval Medical Center San Diego hospital’s cardiac catheterization laboratory” Navy Medicine / Public domain (cropped)
- Related lab (精神神経科学): “Neuroscience 2” Priit Tiganik / CC BY-SA 3.0 (cropped)
- Related lab (認知
行動生理学): “Brain model 12” John Campbell / CC BY 2.0 (cropped)
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