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Diagnostic Reasoning Lab
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A general medicine lab that reaches diagnoses from the medical history and physical examination findings.

AboutAbout the lab
Most outpatient diseases can be diagnosed from the medical history.
Diagnostic Reasoning studies general medicine, which examines undiagnosed symptoms and health problems without limiting the investigation to the organ that causes them.
It is run together with the Department of General Medicine at Chiba University Hospital, and first-visit outpatient consultations are in principle conducted as second-opinion outpatient visits.
Based on the position that most outpatient diseases can be diagnosed from the medical history, it places particular emphasis on the medical interview.
As clinical research, it has also worked on developing a large language model specialized in diagnosing diseases.
Key terms
- General medicine
- Care that does not limit itself to the causative organ and addresses all of a patient's biological, behavioral, and social problems.
- Medical interview
- A conversation in which the clinician learns from the patient how symptoms have progressed and what their life circumstances are, in order to gather clues for diagnosis.
- Large language model
- Artificial intelligence that learns how words connect from large amounts of text, so that it can read and write text.
ResearchResearch themes
The lab centers on general medicine, which approaches undiagnosed symptoms and health problems from an angle not limited to the causative organ. The clinical research page includes research on developing a large language model specialized in disease diagnosis.
View More ↗MembersFaculty
The members of Diagnostic Reasoning consist of faculty, staff physicians, residents in specialty training, senior residents, department secretaries, professors emeritus, and project researchers.As of 2026
- LecturerTakanori Uehara
- Assistant ProfessorYasutaka Yanagita
- Project Assistant ProfessorRurika Sato
- Assistant ProfessorLi Yu
- Project Assistant ProfessorKoichiro Kishimoto
- LecturerTomoko Tsukamoto
- Project ProfessorKiyoshi Shikino
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Middle-aged female doctor talking to a patient during a video consultation at home in a cozy setting” Shixart1985 / CC BY 2.0 (cropped)
- Related lab (Emergency and Critical Care Medicine Lab): “20250808 Intensive care unit bed” Ismael Olea / CC BY 4.0 (cropped)
- Related lab (Medical Informatics Lab): “Libre EHR - features” Nguedia Adele / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Oncology Lab): “Chemotherapy drug” Larry Ostby (Photographer) / Public domain (cropped)
- Related lab (Immune Cell Medicine Lab): “Лаборант готовит индивидуальный иммунологический препарат против рака из крови пациента” Иоанна Чернова / CC BY 4.0 (cropped)
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