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Infectious Disease Pathogenesis Lab
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The lab prepares for the next outbreak by studying the struggle between viruses and the body.
AboutAbout the lab
From understanding the pathogenesis of infectious diseases to preparing for the next pandemic
The Infectious Disease Pathogenesis Lab clarifies how infectious diseases arise, become severe, and spread, based on the interactions between pathogens and hosts.
Established in April 2025, the lab mainly targets acute respiratory infections and zoonotic diseases.
The lab conducts analyses spanning pathology, immunology, virology, epidemiology, and information science, with the aim of leading to the development of vaccines, diagnostics, and treatments.
The lab collaborates with the Department of Infectious Disease Pathology at the National Institute of Infectious Diseases, Japan Institute for Health Security, and with Chiba University's research center for mucosal vaccines.
Key terms
- Zoonotic disease
- A disease that infects both animals and humans, emerging by crossing the boundary between animals and people.
- Mucosal antibody
- An antibody secreted onto mucosal surfaces such as the airways and intestines. Secretory IgA is one example.
- Apicoplast
- An intracellular organelle of malaria parasites and related organisms that originated from a chloroplast.
NewsLab news
View More ↗ResearchResearch themes
The lab seeks to understand the interactions between pathogens and hosts and to clarify the mechanisms of onset, severe progression, and transmission of infectious diseases. It aims to connect its findings to vaccines, diagnostics, treatment, and public health response, and thereby contribute to preparedness for the next infectious disease crisis.
*Illustrative imageVaccine development for respiratory infections
Targeting SARS-CoV-2, influenza virus, and respiratory syncytial virus (RSV), the lab studies the immune responses that suppress infection and viral shedding. It focuses in particular on mucosal antibodies such as secretory IgA, which act in mucosal surfaces such as the airways.
*Illustrative imagePathogenesis of respiratory infections
For respiratory infections with pandemic potential, the lab uses patient specimens and animal models to clarify the mechanisms of onset, severe progression, tissue damage, and immune response, combining pathology, immunology, and virology.
*Illustrative imageTransmission of zoonotic diseases
Targeting severe fever with thrombocytopenia syndrome (SFTS), Mpox, malaria, and other diseases, the lab investigates the factors that determine how disease develops and how easily it is transmitted. It is also searching for animal-derived viruses using public data.
*Illustrative imageEvolution of malaria parasites
The lab studies the function of autophagy-related factors in eukaryotic pathogens such as malaria parasites. It is tracing how this factor works in maintaining the apicoplast, an organelle that originated from a chloroplast, and since when it has played that role.
MembersFaculty
The lab's members are faculty, postdoctoral researchers, international researchers, graduate students, and secretaries.As of 2026
- ProfessorTadaki Suzuki
- Associate ProfessorKengo Saito
- Associate ProfessorSho Miyamoto
- Project Associate ProfessorYuji Shinjo
- Project Associate ProfessorJunna Kawasaki
- Assistant ProfessorHirokazu Sakamoto
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “SARS-CoV-2 scanning electron microscope image” National Institute of Allergy and Infectious Diseases (NIAID) / CC BY 2.0 (cropped)
- Vaccine development for respiratory infections: “Comirnaty Omicron XBB.1.5 vial and influenza vaccine 2023” Whispyhistory / CC BY-SA 4.0 (cropped)
- Pathogenesis of respiratory infections: “MERS Coronavirus Particles ( )” NIAID / CC BY 2.0 (cropped)
- Transmission of zoonotic diseases: “Aedes aegypti biting human” Original author: US Department of Agriculture; then denoised rescaled, enhanced with adaptive denoising filters and minimal resharpening, then unscaled to original resolution, for easier refitting at various resolutions. / Public domain (cropped)
- Evolution of malaria parasites: “Micrograph-thin-blood-smear-with-parasites” OpenFlexure Project / CC BY-SA 4.0 (cropped)
- Related lab (先端データ医科学): “Illumina Hiseq 2000 sequencers, BGI Hong Kong sequencing room” Scotted400 / CC BY 3.0 (cropped)
- Related lab (救急集中治療医学): “20250808 Intensive care unit bed” Ismael Olea / CC BY 4.0 (cropped)
- Related lab (国際粘膜免疫・
病態制御学): “3D structure of secretory IgA2” McortNGHH / CC BY-SA 4.0 (cropped) - Related lab (国際アレルギー粘膜免疫学): “Mast Cell (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
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