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Orthopaedic Surgery Lab
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The lab tackles back and joint pain and spinal cord injury through research directly tied to clinical practice.

AboutAbout the lab
Research tied directly to clinical practice and returned to patients.
The lab studies diseases and injuries of the musculoskeletal system, which supports and moves the body, including the lower back, neck, joints, and limbs.
It has clinical and research groups for the lumbar spine; the cervical spine and spinal cord; rheumatism and the hip; the knee and sports medicine; the shoulder; hand surgery; foot surgery; trauma; and bone metastasis tumors.
Rather than "research for research's sake," the whole lab conducts research that is directly connected to clinical practice and keeps the benefit to patients in mind.
It also takes on new fields, such as performing arts medicine (PAM) for musicians and dancers.
Key terms
- Musculoskeletal system
- The group of body parts that support and move the body, including bones, joints, muscles, and nerves
- Discogenic low back pain
- Low back pain caused by the intervertebral discs, which lie between the bones of the spine
- Spinal cord injury
- A condition in which the spinal cord is damaged by injury, causing paralysis of the limbs and trunk and impaired urination and defecation
NewsLab news
A paper by physicians in the lab on surgical smoke in joint replacement surgery was published in JBJS and selected for the cover
An autumn lab information session for medical students and first-year junior residents was held (11/29)
ResearchResearch themes
The lab conducts a large amount of research on the musculoskeletal system. Its hallmark is that the entire lab works as one on research that is not "research for research's sake" but is directly connected to clinical practice, with a view to benefiting patients.
*Illustrative imageMusculoskeletal Pain
The lab studies the mechanisms of musculoskeletal pain, including low back pain (mainly discogenic low back pain) as well as knee and hip pain. Basic research is carried out across the boundaries of the clinical groups.
*Illustrative imageSpinal Cord Injury
In animal models of spinal cord injury, the lab demonstrated that granulocyte colony-stimulating factor (G-CSF) improves motor paralysis, and it conducted an investigator-initiated clinical trial. Aiming at clinical application, it continues to work on elucidating the pathophysiology and developing new treatments.
*Illustrative imageCartilage Regeneration
Centered on the Knee and Sports group, the lab studies the regeneration of articular cartilage, which does not easily heal back to its original state once damaged. It also puts effort into research on imaging biomarkers that can detect knee osteoarthritis at a very early stage.
*Illustrative imageDiagnostic Imaging
Using techniques such as MRI and ultrasound, the lab is working to make visible the pain that earlier technologies could not detect.
MembersFaculty
The lab's members consist of faculty, graduate students, and senior residents.As of 2026
- ProfessorSeiji Ohtori
- Associate ProfessorNobuyasu Ochiai
- ProfessorTakahisa Sasho
- Associate ProfessorSatoshi Yamaguchi
- LecturerTakane Suzuki
- Clinical Associate ProfessorJunichi Nakamura
- ProfessorSumihisa Orita
- LecturerYusuke Matsura
- Clinical LecturerKazuhide Inage
- Clinical LecturerSatoshi Maki
- Assistant ProfessorEiko Hashimoto
- Project Associate ProfessorYasuhiro Shiga
- Project Associate ProfessorMasahiro Inoe
- Project ProfessorYawara Eguchi
- Project Assistant ProfessorAya Kanazuka
- Project LecturerSeiji Kimura
- Clinical LecturerYuya Kawarai
- Project Assistant ProfessorTakahiro Yamazaki
- Project Assistant ProfessorShotaro Watanabe
- Project Assistant ProfessorRui Hirasawa
- Project Assistant ProfessorTakahisa Hishiya
- Assistant ProfessorTakashi Hozumi
- Project Assistant ProfessorTakuya Sakamoto
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Skeleton-2632153” FotoEmotions / CC0 (cropped)
- Musculoskeletal Pain: “Lateral lumbar x ray” FitBro / CC BY-SA 4.0 (cropped)
- Spinal Cord Injury: “Spine model 3” John Campbell / CC BY 2.0 (cropped)
- Cartilage Regeneration: “Osteoarthritis on X-ray” James Heilman, MD / CC BY-SA 4.0 (cropped)
- Diagnostic Imaging: “MRI-Philips” Jan Ainali / CC BY 3.0 (cropped)
- Related lab (脳神経外科学): “Эндоскоп (ФЦН Тюмень)” Дмитрий Кошелев / CC BY-SA 3.0 (cropped)
- Related lab (呼吸器病態外科学): “3D CT of thorax” Mikael Häggström / CC0 (cropped)
- Related lab (腎臓内科学): “Hemodialysis machine INNOVA” Виталий Поспелов at ru.wikipedia / CC BY-SA 3.0 (cropped)
- Related lab (脳神経内科学): “A Cortical Neuron In Isolation” Dchordpdx / CC BY 4.0 (cropped)
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