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International Institute for Integrative Sleep Medicine (WPI-IIIS) Greene-Vogt Lab
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A lab that explores neural activity in the brain during deep slow-wave sleep.

AboutAbout the lab
Exploring what happens in the brain during deep sleep
The Greene-Vogt Lab studies neural activity in the brain during slow-wave sleep, which is regarded as the deepest of the sleep stages.
During slow-wave sleep, groups of neurons in the cortex show strongly synchronized on (active) and off (silent) states, producing a characteristic pattern in the EEG.
Neural activity in the on state closely resembles that of wakefulness, but recent studies from this lab have revealed important differences.
The lab examines cortical neurons and their networks during slow-wave sleep in detail.
Key terms
- Slow-wave sleep
- The sleep stage regarded as the deepest. It is thought to be important for restoring brain function.
- On (active) and off (silent) states
- The states in which groups of cortical neurons are active and silent. During slow-wave sleep, the switching between them becomes strongly synchronized.
ResearchResearch themes
Even a slight lack of sleep greatly reduces efficiency in everyday tasks such as driving, but sleep allows recovery from that state. Particularly deep slow-wave sleep is thought to be important for restoring brain function, and the lab investigates cortical neurons and networks during slow-wave sleep.
View More ↗MembersFaculty
- ProfessorRobert Greene
- Associate ProfessorKaspar Vogt
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Unbonnetalectrodes” Simon Fraser University - Communications & Marketing / CC BY 2.0 (cropped)
- Functions and Regulation of Neural Activity During Slow-Wave Sleep: “Cortical Neurons, stained” Ns takes photos / CC BY 4.0 (cropped)
- Related lab (国際統合睡眠医科学研究機構(WPI-IIIS) 柳沢/船戸研究室): “Mother and newborn sleeping on a bamboo bed near a campfire in a house in Don Det Laos” Basile Morin / CC BY-SA 4.0 (cropped)
- Related lab (国際統合睡眠医科学研究機構(WPI-IIIS) 戸田研究室): “Drosophila vials” J. Albert Vallunen (albval) / CC BY-SA 2.5 (cropped)
- Related lab (国際統合睡眠医科学研究機構(WPI-IIIS) 阿部研究室): “International Institute for Integrative Sleep Medicine, Jan 06, 2017” Keiina / CC BY-SA 4.0 (cropped)
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