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Medical Virology Lab (Japan Institute for Health Security, JIHS)
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A lab that unravels how viruses evade immunity and designs antibody therapeutics and vaccines.
AboutAbout the lab
Unraveling how viruses evade immunity.
The Medical Virology Lab, at the Japan Institute for Health Security (JIHS), studies viral infections prone to antigenic variation, such as COVID-19 and influenza.
The lab works to clarify the mechanism of "immune evasion," by which viruses escape the immune system, and conducts research on profiling immunity that is also effective against these infections.
By combining immune profiling, structural biology, and computational science, the lab aims to design antibody therapeutics and vaccines.
The lab is a cooperative graduate school lab of the Medical Sciences Degree Program in the Degree Programs in Comprehensive Human Sciences at the University of Tsukuba, and supervises graduate students.
Key terms
- Immune evasion
- When a virus changes and slips past the body's immune defenses.
- Structural biology
- The field that studies the three-dimensional shapes of proteins and other molecules in order to understand how they function.
- Antibody therapeutics
- Drugs made by using the action of antibodies that bind to pathogens and other targets.
ResearchResearch themes
The lab aims to clarify the mechanisms of immune evasion in viral infections prone to antigenic variation. It also conducts research on profiling immunity that is effective against these infections, and designs antibody therapeutics and vaccines using methods that combine structural biology and computational science.
View More ↗MembersFaculty
- Academic AdvisorYoshimasa Takahashi
- ProfessorAtsushi Kawaguchi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Colorized scanning electron micrograph of a cell (teal) infected with SARS-CoV-2 virus particles (orange), isolated from a patient sample” NIAID / CC BY 2.0 (cropped)
- Related lab (Drug Discovery and Infection Control Lab (Japan Institute for Health Security, JIHS)): “Colorized transmission electron micrograph of rabies virus particles (green) image captured at the NIAID Integrated Research Facility in Fort Detrick, Maryland - 7” NIAID / CC BY 2.0 (cropped)
- Related lab (Cell and Molecular Engineering Lab (National Institute of Advanced Industrial Science and Technology, AIST)): “Beckman Coulter Ultracentrifuge” Karbohut / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Drug Discovery Lab (Eisai Co., Ltd. Tsukuba Research Laboratories)): “Gravity liquid chromatography column-01” Lilly_M / CC BY-SA 3.0 (cropped)
- Related lab (Translational Science for Drug Discovery Lab (Astellas Pharma Inc.)): “Micro-pipette used by Lord Joseph Lister in his experiments on souring milk” Science Museum, London / CC BY 4.0 (cropped)
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