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Cancer Immunotherapy Research Lab
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A lab that researches next-generation cancer treatment using immune cells.
AboutAbout the lab
Next-generation cancer treatment using immune cells.
The lab conducts research and development aimed at realizing next-generation cancer immunotherapy that uses immune cells.
It belongs to the Drug Discovery Support Research Division of the Transborder Medical Research Center.
The lab studies immunotherapy using gene-modified immune cells, such as CAR-T cell therapy and TCR-T cell therapy, as well as immunotherapy using iPS cells.
In addition to basic research, such as searching for new cancer treatment targets and analyzing how immune cells attack tumors, the lab also works on research into cell manufacturing aimed at clinical practice.
Key terms
- CAR-T cell therapy
- A type of cancer immunotherapy that uses gene-modified immune cells. It is a representative example, along with TCR-T cell therapy.
- iPS cells
- Artificial stem cells that can turn into many different types of cells. In this field, they are used as the source material for making immune cells.
- Cell Processing Facility (CPF)
- A facility for producing cell products for regenerative medicine products. It is used to prepare approved products and investigational products for clinical trials.
ResearchResearch themes
Toward effective cancer immunotherapy, the lab advances research and development at each step: basic, applied, and clinical. Its focus is next-generation cancer immunotherapy using immune cells, and it also conducts research on cell manufacturing aimed at clinical practice.
*Illustrative imageResearch and development of cancer treatment using immune cells
The lab researches and develops immunotherapy using gene-modified immune cells, such as CAR-T cell therapy and TCR-T cell therapy, and using iPS cells. Its work includes searching for cancer treatment targets, analyzing antitumor mechanisms, and enhancing efficacy through gene editing. It is also developing cancer-on-a-chip systems that evaluate efficacy without using animals.
*Illustrative imageA cell processing facility supporting regenerative medicine
The lab also runs the Regenerative Medicine Promotion Office and manages the Cell Processing Facility (CPF), which produces cell products. The CPF is used to prepare approved regenerative medicine products and investigational products for clinical trials, and a dedicated facility called TACT has also been built at the university hospital.
MembersFaculty
- ProfessorShin Kaneko
- Assistant ProfessorYuta Mishima
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Laminaar TYKI DL20221105” Darja.Lavogina / CC BY-SA 4.0 (cropped)
- Research and development of cancer treatment using immune cells: “Scanning electron micrograph of a human H9 T cell infected with HIV virus particles” NIAID / CC BY 2.0 (cropped)
- A cell processing facility supporting regenerative medicine: “Biosafety Cabinet” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Oncology Lab): “Oncology ward” Lovelyn Obiakor / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Research and Regional Innovation Lab): “Krankentransportwagen in Passau” High Contrast / CC BY 3.0 de (cropped)
- Related lab (Connective Tissue Disease, Rheumatology, and Allergy Lab): “U.S. Air Force Staff Sgt. Thomas C. Sullivan Jr., a laboratory technician assigned to the 319th Medical Support Squadron, places a medical sample into a test tube rack at the medical laboratory on Grand Forks 130522-F-JB669-061” Staff Sgt. Luis Loza Gutierrez / Public domain (cropped)
- Related lab (Clinical Trials and Clinical Epidemiology Lab): “FP111 A4 medical record file (UK)” Whispyhistory / CC0 (cropped)
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