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Neuroinformatics Lab
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A lab that analyzes brain activity data to uncover how the brain works.
AboutAbout the lab
Exploring new techniques from brain data.
The Neuroinformatics Lab studies how the brain works by analyzing recorded data on the activity of the brain and neurons.
The lab aims to offer artificial intelligence and robotics a new perspective, drawn from the internal mechanisms of the brain that emerge from neuroscience data analysis.
The lab is also building an experimental environment that analyzes the EEG of sleeping mice in real time and uses optogenetics to control the activity of specific neurons.
This experimental system is being built in collaboration with the Sakaguchi Lab at the International Institute for Integrative Sleep Medicine, University of Tsukuba.
Key terms
- Optogenetics
- A method that uses light-sensitive proteins to control only a specific population of neurons with light in the brain of a living animal.
- Calcium imaging
- A method for studying neuronal activity from videos of the brain of a live mouse recorded with a miniature microscope.
- Spike train
- The action potentials (spikes) emitted by a neuron, arranged in order of time.
- Kernel
- A function of two variables that returns a single value from two pieces of data. It is used in kernel methods in machine learning.
ResearchResearch themes
Findings from neuroscience have inspired many developments in artificial intelligence, such as neural networks and reinforcement learning. The lab aims to offer artificial intelligence and robotics a new perspective, drawn from the internal mechanisms of the brain revealed by the analysis of neuroscience data.
*Illustrative imageBrain Manipulation Experiments Using Optogenetics
The lab is building an environment that analyzes high-resolution EEG in real time. Only during a specific sleep stage, a laser is applied to the mouse brain to suppress a specific population of neurons, in order to investigate the activity during sleep that is necessary for memory consolidation.
*Illustrative imageAutomatic Classification of Sleep Stages
The lab is developing software that classifies sleep stages in real time in 4-second units, using only single-channel EEG from mice. Combined with manipulations such as optogenetics, it can be used to causally investigate the role of whole-brain states.
*Illustrative imagePattern Discovery from Calcium Imaging
The lab applies image processing and pattern recognition to calcium imaging videos recorded from the brains of live mice with a miniature microscope. It is developing software that automatically finds ensembles and motifs, in which multiple neurons are active in synchrony.
*Illustrative imageKernels for Multichannel Spike Trains
Defining a kernel on spike trains makes it possible to apply kernel methods from machine learning to them. The lab studies kernels not on a single spike train but on many spike trains (multichannel spike trains).
MembersFaculty
The members of the Neuroinformatics Lab consist of faculty and students in the doctoral and master's programs.
- ProfessorTaro Tezuka
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Young blonde white girl sleeping on the side” Alexandre Bernier Marceau / CC BY-SA 4.0 (cropped)
- Brain Manipulation Experiments Using Optogenetics: “Neuroscience 2” Priit Tiganik / CC BY-SA 3.0 (cropped)
- Automatic Classification of Sleep Stages: “Polysomnography model” Clinique Somnomed / CC BY-SA 4.0 (cropped)
- Pattern Discovery from Calcium Imaging: “Artificial neural network” Geetika saini / CC BY-SA 4.0 (cropped)
- Kernels for Multichannel Spike Trains: “Hameg Oscilloscope HMO3004 Series” Ordercrazy / CC0 (cropped)
- Related lab (機械知能研究室): “Unraveling AI Complexity - A Comparative View of AI, Machine Learning, Deep Learning, and Generative AI” PopovaZhuhadar / CC BY-SA 4.0 (cropped)
- Related lab (マニピュレーション・システム研究室): “Robotic ROV Manipulator Arm” BPLINFO / CC BY-SA 4.0 (cropped)
- Related lab (脳情報システム研究室): “Juggling Balls (81706016)” Richard Leonard / CC BY 2.0 (cropped)
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