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Supramolecular Chemistry Lab
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A supramolecular chemistry lab that uses ring-shaped molecules to recognize and capture target molecules with precision.

AboutAbout the lab
Designing artificial receptors that recognize molecules with precision
The Nakamura Lab (Supramolecular Chemistry) studies "supramolecules," designing and synthesizing original cyclic multimers to create new materials.
Natural receptors such as proteins select and bind specific molecules in pockets surrounded by many amino acids, combining relatively weak interactions such as hydrogen bonds.
The lab develops artificial receptors that achieve precise molecular recognition through two approaches: assembling metal complex units and making the building blocks asymmetric.
Such molecules are expected to lead to applications in sensors, separation and purification, and selective reactions.
Key terms
- Artificial receptor
- An artificially designed molecule that selects and binds target molecules, like a natural receptor
- Macrocyclic complex
- A cyclic metal complex that gathers metal coordination sites in the inner cavity of a rigid framework
- Coordination bond
- A bond formed between a metal and a molecule. It has high bond energy and is reversible and highly chemoselective
NewsLab news
A master's student won an Encouragement Award at the 14th TIA Nano-Green Summer School
A doctoral student won the TCI Poster Award at the 36th Symposium on Basic Organic Chemistry
A doctoral student won a BCSJ Award at the 57th Summer School of the Young Researchers' Group for Structural Organic Chemistry
A doctoral student won an Excellent Poster Award at the 23rd Host–Guest and Supramolecular Chemistry Symposium
Prof. Nakamura has been selected to receive the SHGSC Japan Award of Excellence 2026
ResearchResearch themes
The lab works on developing artificial receptors that recognize molecules by arranging many interaction sites asymmetrically, as natural receptors do. Using coordination bonds with metals and asymmetric structures, the lab designs and synthesizes molecules with many interaction sites.
*Illustrative imageMolecular capture with assembled metal complexes
Coordination bonds with metals have high bond energy, are reversible, and are highly chemoselective, which makes them a promising means of capturing molecules. The lab has developed macrocyclic complexes that gather metal coordination sites in the inner cavity of a rigid framework, and studies their functions.
*Illustrative imagePrecise recognition with asymmetric receptors
Most existing artificial receptors are homo-multimers made of identical repeating units. The lab has developed artificial receptors with an asymmetric structure that keeps the same units but differentiates each one, and studies them as molecules that can achieve precise multipoint recognition.
MembersFaculty
The members of the Nakamura Lab are faculty members, commissioned researchers from overseas, doctoral and master's students, and undergraduate thesis students.As of 2026
- ProfessorTakashi Nakamura
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Osmium Host-Guest Assembly” Dslate2123 / CC BY-SA 3.0 (cropped)
- Molecular capture with assembled metal complexes: “Na8Si46 inorganic clathrate structure with coordination polyhedra” PickledSquid / CC BY-SA 4.0 (cropped)
- Precise recognition with asymmetric receptors: “Supramolecular Assembly Lehn” M stone at English Wikipedia / CC BY-SA 3.0 (cropped)
- Related lab (Inorganic Synthetic Chemistry Lab): “Pigments in test tubes in UCL Chemistry - London, United Kingdom” UCL Mathematical and Physical Sciences from London, UK / CC BY 2.0 (cropped)
- Related lab (Functional Materials Chemistry Lab): “Scrutinyite crystal structure (Wyckoff 1963) polyhedra model on (001)” Ra'ike (Wikipedia) / CC0 (cropped)
- Related lab (Bioorganic Chemistry Lab): “Separatory funnel” 作者不詳 / Public domain (cropped)
- Related lab (Inorganic Reaction Chemistry Lab): “Winkler Titration Prior Titration” Original uploader was Willwood at en.wikipedia / CC BY-SA 3.0 (cropped)
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