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Biological Regulation Systems Lab
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The lab elucidates how organelles function and connects that knowledge to drug discovery.
AboutAbout the lab
Understanding life through organelles and linking it to drug discovery
The Biological Regulation Systems Lab (the Shiiba Lab) studies how organelles function, looking at their connections within cells and between organs and tissues.
The lab seeks to elucidate at the molecular level how organelles such as mitochondria and the endoplasmic reticulum coordinate with one another in cells, and how this mechanism differs from organ to organ.
The lab aims to clarify the molecular basis of diseases involving the breakdown of organelle function, and to use this to identify new drug targets and develop therapeutic strategies.
The lab was established in April 2026 at the Graduate School of Pharmaceutical Sciences, Tohoku University.
Key terms
- Organelle
- Also called a cell organelle. A structure inside a cell that has its own role, such as mitochondria and the endoplasmic reticulum
- Mitochondria
- One type of organelle (cell organelle) in cells. Together with the endoplasmic reticulum and others, they are involved in maintaining homeostasis in the body
- Drug target
- A molecule or other component in the body on which a drug acts. It is the point to aim at when developing a new drug
NewsLab news
View More ↗ResearchResearch themes
The human body is made of cells, and the organelles inside cells play important roles in maintaining homeostasis. The lab aims to elucidate at the molecular level how organelles coordinate with one another and how this differs from organ to organ, and to connect this to understanding disease and to drug discovery.
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MembersFaculty
The members of the Biological Regulation Systems Lab consist of faculty and researchers.As of 2026
- Assistant ProfessorIsshin Shiiba
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Red Fluorescence Microscopy” Jamil Baza / CC BY 4.0 (cropped)
- Organelle coordination and differences between organs: “Unlabeled Animal Cell” Conrad 7 / CC0 (cropped)
- Related lab (分子細胞生化学分野): “NEUROTENSIN RECEPTOR 2” rcsb pdb / CC BY 4.0 (cropped)
- Related lab (生物構造化学分野): “Optical microscope for the study of paint fragments” Froselong / CC BY-SA 4.0 (cropped)
- Related lab (衛生化学分野): “Onion cells under the fluorescence microscope 3” Kateryna Kot / CC BY-SA 4.0 (cropped)
- Related lab (分子イメージング薬学分野): “Radioactive Syringe and Shield” Thirteen Of Clubs from Minneapolis / CC BY-SA 2.0 (cropped)
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