LAB LOGA page on LabLog, a review site (not the lab's official page)
Advanced Free Radical Control Joint Research Lab
Machine-translated · View original
A lab that researches and develops dental disinfection technologies using radicals generated by light.
AboutAbout the lab
Using light-generated radicals for dental disinfection
The Advanced Free Radical Control Joint Research Lab studies how to apply the disinfecting action of reactive oxygen species generated by light to dental treatment.
The lab researches disinfection technologies that shine light on hydrogen peroxide, a disinfectant, or on polyphenols found in plants to generate hydroxyl radicals.
Using this technology, the lab developed a periodontal disease treatment device and demonstrated its efficacy and safety in an investigator-initiated clinical trial.
The lab also evaluates materials for prosthetic devices made with dental CAD/CAM technology.
Key terms
- Hydroxyl radical
- A type of reactive oxygen species. It is extremely reactive and is the main agent that oxidizes and kills bacteria
- Investigator-initiated clinical trial
- A trial in which physicians themselves plan and conduct the study to confirm the efficacy and safety of a new medical device or similar product in humans
- CAD/CAM
- A technology in which a design is made on a computer and a machine mills it from a block of material to make items such as dental crowns
- Prosthetic device
- A device, such as a crown, used to replace or restore a missing or damaged tooth
NewsLab news
A paper by Professor Takahashi and colleagues was published in the Journal of Dental Research
Assistant Professor Shishido received the "NOF Travel Grant (selected)" (IADR Scandinavian Division (N…
A paper by Professor Nakamura and colleagues was published in the Journal of Dental Research
Together with Luke Co., Ltd., the lab received the Minister of Health, Labour and Welfare Award at the Japan Open Innovation Prize
A press release was issued on the social implementation of Perimil and Blue Radical P-01
ResearchResearch themes
The lab researches dental treatment and oral hygiene management technologies that apply the disinfecting action of hydroxyl radicals generated by light. It also evaluates the strength, biocompatibility, and other properties of prosthodontic materials.
*Illustrative imageDeveloping dental devices that use radical disinfection
Shining blue light on hydrogen peroxide, a disinfectant, generates hydroxyl radicals. The lab researches local disinfection technology that uses this disinfecting action, and has developed a periodontal disease treatment device whose efficacy and safety were shown in an investigator-initiated clinical trial.
*Illustrative imageDisinfection technology using polyphenols
The lab focuses on the fact that when ultraviolet light is shone on polyphenols, they show a pro-oxidant action, the opposite of their antioxidant action. This research and development applies disinfection technology based on this reaction as a new treatment for dental caries and as a new oral hygiene management method.
*Illustrative imageEvaluating the properties of prosthodontic materials
The lab examines the strength, fatigue resistance, biocompatibility, and bacterial adhesion of prosthetic devices milled from zirconia and composite resin. In non-clinical studies, it has demonstrated that CAD/CAM zirconia crowns and resin crowns are strong enough to be used even in the molar region.
MembersFaculty
The members of the Advanced Free Radical Control Joint Research Lab consist of faculty members, academic researchers, part-time lecturers at the graduate school, and joint researchers.As of 2026
- ProfessorKeisuke Nakamura
- Professor (Concurrent)Taro Kanno
- Specially Appointed Professor (Concurrent)Nobuhiro Takahashi
- LecturerMidori Shirato
- Assistant ProfessorKirika Ishiyama
- Assistant ProfessorShunichi Shishido
- Assistant ProfessorSirus Safaei
- Assistant ProfessorRaju Kumar Parajuli
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Advanced Free Radical Control Joint Research Lab
Molecular and Regenerative Prosthodontics LabFaculty of Dentistry, School of DentistryCrown and bridge prosthodontics: digital dentistry, CAD/CAM …
Next-Generation Dental Materials Engineering Joint Research LabFaculty of Dentistry, School of DentistryDevelopment of next-generation dental materials and devices …
Endodontology and Periodontology LabFaculty of Dentistry, School of DentistryEndodontics and periodontology; elucidation of the onset and…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “US Navy 050920-N-3188P-008 U.S. Navy Dental Technician 2nd Class Barbara J. Edenfield, assigned to Naval Branch Health Clinic Jacksonville, waxes a hard night guard” U.S. Navy photo by Photographer's Mate 2nd Class Jamar X Perry / Public domain (cropped)
- Developing dental devices that use radical disinfection: “Blue LED Filament Lamp” EVcollie / CC BY-SA 4.0 (cropped)
- Disinfection technology using polyphenols: “Jakseol green tea leaves 2” 예향 / CC BY 2.0 kr (cropped)
- Evaluating the properties of prosthodontic materials: “Single Unit Zirconia Anterior Dental Crown” James Roback, UticaDentalLab / CC BY-SA 4.0 (cropped)
- Related lab (Molecular and Regenerative Prosthodontics Lab): “Disc with dental implants made with WorkNC” Sescoi CAD/CAM / CC BY-SA 2.0 (cropped)
- Related lab (Next-Generation Dental Materials Engineering Joint Research Lab): “Blade dental implant” Hanabishi / CC BY-SA 3.0 (cropped)
- Related lab (Endodontology and Periodontology Lab): “A dental chair in a dentist clinic in North Carolina, United States” Harrison Keely / CC BY 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.