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Regenerative Dental Engineering Lab
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The lab addresses challenges in clinical dentistry from the perspective of regenerative biomedical engineering.
AboutAbout the lab
Solving dental challenges through regenerative biomedical engineering.
The Regenerative Dental Engineering Lab focuses on unresolved problems in clinical dental practice and conducts research to solve them from the perspective of regenerative biomedical engineering.
Applying techniques for modifying titanium nano-surfaces and for regulating intracellular redox, the lab has been developing biomaterials that enable regeneration of the bone and periodontal tissue around implants and control of inflammation.
The lab also focuses on the mechanical stimuli that cells receive, and uses mechanobiology to uncover the mechanisms of diseases caused by occlusal and masticatory forces.
The lab also develops dental devices and educational support systems that combine AI and computer engineering.
Key terms
- Mechanobiology
- The field that studies how forces applied to cells and tissues affect their function and disease
- Redox
- Oxidation and reduction reactions. The oxidation-reduction balance inside a cell is involved in how the cell functions
- Biomaterial
- A material that comes into contact with the body or is used inside it. Here, it refers to materials that help regenerate bone and periodontal tissue
ResearchResearch themes
The lab aims to solve unresolved problems in clinical dental practice from the perspective of regenerative biomedical engineering. Focusing on titanium nano-surfaces, intracellular redox regulation, and the mechanical stimuli that cells receive, it works on tissue regeneration, control of inflammation, and elucidation of disease mechanisms.
*Illustrative imageElucidating diseases involving occlusal and masticatory forces
The lab analyzes cellular responses to mechanical stimuli and the resulting changes in disease states from a mechanobiology perspective. It aims to build a foundation for personalized dental treatment.
*Illustrative imageRegeneration and disease control with nanomaterials
Through material design that makes use of nanostructures, the lab aims to develop biomaterials that can achieve both regeneration of target tissue and control of inflammation.
*Illustrative imageDiagnostic devices using nanotechnology
The lab works on creating intraoral diagnostic devices and biofunctional chips that detect minute biological reactions with high sensitivity, enabling early diagnosis of disease and prediction of prognosis.
*Illustrative imageIntracellular redox regulation and tissue regeneration
The lab regulates cell function by adjusting the oxidation-reduction balance, and pursues the elucidation and application of molecular mechanisms that can induce regeneration and suppress inflammation.
MembersFaculty
- ProfessorMasahiro Yamada
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dental-implant-illustration” Alexmit art / CC BY-SA 4.0 (cropped)
- Elucidating diseases involving occlusal and masticatory forces: “Molar relationship” Rjmedink / CC BY-SA 4.0 (cropped)
- Regeneration and disease control with nanomaterials: “Rastersondenmikroskop, Christine Möller SNI” Christine Möller, SNI / CC BY-SA 4.0 (cropped)
- Diagnostic devices using nanotechnology: “Microfluidic chip for point-of-care medical devices” FMNLab / CC BY 4.0 (cropped)
- Intracellular redox regulation and tissue regeneration: “Scientist checks cell culture flask on microscope” Peter Saxon / CC BY-SA 4.0 (cropped)
- Related lab (生体材料理工学分野): “Laboratory of Biomaterials” Berillo D / CC BY-SA 4.0 (cropped)
- Related lab (分子・再生歯科補綴学分野): “Disc with dental implants made with WorkNC” Sescoi CAD/CAM / CC BY-SA 2.0 (cropped)
- Related lab (口腔システム補綴学分野): “Dental implants” Tiia Monto / CC BY 4.0 (cropped)
- Related lab (顎口腔矯正学分野): “Gipsabguss Gebiss” Sciencia58 / CC0 (cropped)
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