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Conservative Dentistry Lab
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A lab that researches tooth-preserving treatment techniques and regenerative medicine.
AboutAbout the lab
Achieving world-leading research that reaches practical use
The lab provides education centered on conservative treatment, including operative dentistry and endodontics, and conducts research aimed at realizing regenerative medicine.
It is building a new kind of conservative dentistry that combines the etiology and treatment techniques of traditional conservative dentistry with basic knowledge of regenerative medicine.
Its research is built around three axes, bone regeneration, inflammation and endodontics, and oral and systemic health management, and takes up problems that dentists face in clinical practice.
The lab also collaborates with the Faculty of Engineering and the School of Medicine, aiming to bring its research results into practical use.
Key terms
- Endodontics
- Endodontics: treatment of diseases of the nerves and blood vessels inside the tooth. It includes root canal treatment, in which the inside of the root is cleaned and disinfected.
- Apical periodontitis
- Apical periodontitis: a disease in which bacterial infection from a cavity causes the jawbone around the tip of the tooth root to break down.
- Apicoectomy
- Apicoectomy (root-end resection): a surgical operation that removes the tip of the tooth root.
ResearchResearch themes
The lab aims to create a new kind of conservative dentistry that combines tooth-preserving treatment techniques with basic knowledge of regenerative medicine. Its research centers on bone regeneration, inflammation and endodontics, and oral and systemic health management, and it works toward solving problems in clinical dentistry and putting the solutions to practical use.
*Illustrative imageBone regeneration by osteoblast transplantation
For horizontal bone defects caused by periodontal disease, the lab researches and develops a regenerative medicine product that combines osteoblasts, isolated from jawbone using its own technique, with a scaffold material developed jointly with the National Institute of Advanced Industrial Science and Technology (AIST).
*Illustrative imageTreatment resistance in apical periodontitis
To understand apical periodontitis from an immunological perspective and to create new anti-inflammatory treatments that suppress inflammation, the lab is clarifying the mechanisms of local inflammation in the tissue around the root apex and searching for the molecules that make treatment less effective.
*Illustrative imageDevelopment of new root canal irrigation techniques
The lab studies how effectively various root canal irrigants remove the biofilm inside the tooth root that is seen in apical periodontitis.
*Illustrative imageApicoectomy using anti-inflammatory therapy
In collaboration with Tokyo Medical and Dental University, Osaka University, and Niigata University, the lab is developing a technique that, after apicoectomy, directly stimulates and activates stem cells in the periodontal tissue at the root apex with cytokines, so that bone and periodontal ligament regenerate functionally.
MembersFaculty
The members of the lab consist of faculty, part-time lecturers, clinical staff dentists, PhD students (including working-professional graduate students), research students, technical assistants, administrative staff, and resident dentists.
- ProfessorMasahiro Saito
- Clinical ProfessorTsuneyasu Izawa
- Associate ProfessorYoshio Yahata
- LecturerYuya Kamano
- Assistant ProfessorMasafumi Kanehira
- Research Assistant ProfessorMoe Sandar Kyaw
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dental tools and equipment arranged neatly on a clinical workstation at a modern dental clinic” Shixart1985 / CC BY 2.0 (cropped)
- Bone regeneration by osteoblast transplantation: “3D-Printed Biodegradable Human Bone Scaffold 4” Donvikro / CC BY-SA 4.0 (cropped)
- Treatment resistance in apical periodontitis: “Abscessed tooth periapical radiograph” Coronation Dental Specialty Group / CC BY-SA 3.0 (cropped)
- Development of new root canal irrigation techniques: “Dental root canal treatment process 3” Suyash.dwivedi / CC BY-SA 4.0 (cropped)
- Apicoectomy using anti-inflammatory therapy: “Endodontics microscope” Endodontist NYC / CC BY-SA 4.0 (cropped)
- Related lab (歯内歯周治療学分野): “A dental chair in a dentist clinic in North Carolina, United States” Harrison Keely / CC BY 4.0 (cropped)
- Related lab (顎顔面口腔再建外科学分野): “Implant overdenture model” Coronation Dental Specialty Group[1] / CC BY-SA 3.0 (cropped)
- Related lab (分子・再生歯科補綴学分野): “Disc with dental implants made with WorkNC” Sescoi CAD/CAM / CC BY-SA 2.0 (cropped)
- Related lab (生体材料理工学分野): “Laboratory of Biomaterials” Berillo D / CC BY-SA 4.0 (cropped)
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