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Clinical Oncology Lab
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A medical oncology lab aiming for care that gives cancer patients hope.

AboutAbout the lab
Learning from patients, learning more, and giving back to patients.
Medical Oncology is a clinical department of Tohoku University Hospital that upholds the idea of "creating a society where everyone can live with peace of mind and hope, even with cancer."
The lab aims to provide care that lets all cancer patients keep their hope, and to keep creating new treatment options.
In the member introductions, the professor states that the department carries out clinical care and research with the attitude of "learning from patients, learning more, and giving back to patients."
The department accepts applications from students and residents for hospital visits.
Key terms
- Medical oncology
- Medical oncology: the field of internal medicine that provides care for cancer
- BRAF
- One of the important cancer-related genes (oncogenes), in which mutations are found in many cancers
- Multi-omics analysis
- Multi-omics analysis: analysis that integrates data on several types of biomolecules, such as the genome and proteins
ResearchResearch themes
Medical Oncology upholds providing care that lets all cancer patients keep their hope and creating new treatment options. Research differs by lab and covers the development of new anticancer drugs, analysis of genetic mutations in cancer, analysis of abnormal DNA methylation, and the tumor microenvironment and immunotherapy.
*Illustrative imageDevelopment of new anticancer drugs
The lab evaluates the activity of anticancer drug candidates and analyzes their mechanisms of action, and also applies drug delivery system technology, aiming for new anticancer drugs with fewer side effects. It also investigates how antibiotics and gut bacteria affect the efficacy of anticancer drugs.
*Illustrative imageNew treatments for BRAF-mutant cancers
BRAF-mutant colorectal cancer has a poor prognosis, and new treatment strategies are needed. The lab searches for new target genes and inhibitory compounds that can enhance the effect of BRAF-targeted molecular therapy or overcome resistance to it.
*Illustrative imagePersonalized treatment of rare cancers
Rare cancers and cancers of rare molecular subtypes have few cases, and effective treatments are limited. Using large-scale genomic data, the lab analyzes how the characteristics of genetic mutations affect patient prognosis and response to treatment.
*Illustrative imageDNA methylation research in colorectal cancer
The lab conducts translational research focused on epigenetic abnormalities in colorectal cancer, especially abnormal DNA methylation. Through multi-omics analysis of clinical specimens and large-scale databases, it aims to develop new biomarkers and treatment strategies.
MembersFaculty
Members of Medical Oncology include faculty, hospital staff physicians, graduate students, and co-medical staff (CRC nurses, technical assistants, and administrative assistants), as well as Professors Emeritus, staff on long-term assignment, and part-time lecturers.As of 2026
- ProfessorHisato Kawakami
- Associate ProfessorHidekazu Shirota
- LecturerKen Saijo
- Assistant Professor (Hospital Lecturer)Keigo Komine
- Assistant Professor (Hospital Lecturer)Kota Ochi
- Assistant ProfessorYuki Yoshino
- Assistant ProfessorYuki Kasahara
- Assistant ProfessorSakura Taniguchi
- Assistant ProfessorYuya Yoshida
- Project AssistantShonosuke Wakayama
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “I V drip ( )” Laurel L. Russwurm from Canada / CC BY 2.0 (cropped)
- Development of new anticancer drugs: “Chemotherapy vials (4)” Bill Branson (Photographer) / Public domain (cropped)
- New treatments for BRAF-mutant cancers: “Protein BRAF PDB 1uwh” Emw / CC BY-SA 3.0 (cropped)
- Personalized treatment of rare cancers: “DNBSEQ-G50” RPSkokie / CC BY-SA 4.0 (cropped)
- DNA methylation research in colorectal cancer: “20251019 Replica DNA double helix model Berlin 04” Flocci Nivis / CC BY 4.0 (cropped)
- Related lab (Center for Regional Cancer Care Promotion): “Waiting area, Quilpie Hospital, Queensland, 2024, 01” Kgbo / CC BY-SA 4.0 (cropped)
- Related lab (Hematology Lab): “Myeloid leukemia” Makysm / CC0 (cropped)
- Related lab (Nephrology Lab): “Dialysis unit of CKD & Urology Hospital” Yahya / CC BY-SA 4.0 (cropped)
- Related lab (Emergent Medicine Lab (SiRIUS Institute of Medicine)): “Barbara McClintock ( ) shown in her laboratory in 1947” Smithsonian Institution/Science Service; Restored by Adam Cuerden / Public domain (cropped)
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