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Higher Brain Dysfunction Lab
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A clinical department that explores higher brain dysfunction and dementia through both patient care and research.
AboutAbout the lab
Exploring higher brain dysfunction and dementia through both patient care and research.
The Higher Brain Dysfunction Lab studies both higher brain dysfunction and dementia, which arise after brain diseases or injuries, through patient care and research.
Higher brain functions are the complex neural functions that make us human, such as attention, memory, language, visuospatial cognition, and executive function.
The lab rests on three pillars: higher brain dysfunction caused by focal brain damage, dementia, and higher brain dysfunction in epilepsy.
In 1994, it was founded at Tohoku University as the first clinical department in Japan specializing in this field.
Key terms
- Higher brain dysfunction
- A condition in which attention, language, memory, and other functions are impaired after a brain disease or injury, causing difficulty in social life
- Focal brain damage
- Damage to one part of the brain caused by a brain disease or injury. Different higher brain dysfunctions occur depending on the damaged region
- Epilepsy
- A disease in which abnormal brain function causes repeated excessive neural excitation in the brain
- Neuropsychological tests
- Tests used to assess the symptoms of higher brain dysfunction
ResearchResearch themes
The lab conducts research on diagnosing higher brain dysfunction and dementia, and on elucidating their pathology. Its research begins with careful examination and treatment of each individual patient.
*Illustrative imageResearch combining symptoms, imaging, and physiology
The lab integrates neuropsychological tests to assess symptoms, neuroimaging methods to identify the neural basis, and neurophysiological methods to assess neural function. The lab explains that its findings on dementia with Lewy bodies and idiopathic normal pressure hydrocephalus are widely useful in clinical practice.
*Illustrative imageResearch on how higher brain functions work
The lab studies the mechanisms of higher brain functions that underlie the human mind, in collaboration with a wide range of researchers in physiology, informatics, engineering, linguistics, and other fields.
MembersFaculty
The members of the lab consist of faculty, academic researchers, part-time physicians, doctoral students, and secretaries.As of 2025
- ProfessorHidenori Endo
- Associate ProfessorShigenori Kanno
- Assistant ProfessorShoko Ota
- Assistant ProfessorNobuko Kawakami
- Assistant ProfessorKazuo Kakinuma
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Torre-di-londra” Gcappellotto / CC BY-SA 3.0 (cropped)
- Research combining symptoms, imaging, and physiology: “Vantage Atlas MRI scanner from Toshiba” Mos.ru / CC BY 4.0 (cropped)
- Research on how higher brain functions work: “Brain model 12” John Campbell / CC BY 2.0 (cropped)
- Related lab (Neurology Lab): “PET MRI Scanner (NIH BioArt )” Courtesy of NIAID Malcolm Houston / Public domain (cropped)
- Related lab (Clinical Aging Medicine Lab (Institute of Development, Aging and Cancer)): “Brain MRI 0145 02” Nevit Dilmen (talk) / CC BY-SA 3.0 (cropped)
- Related lab (Biological Systems Physiology Lab): “Close-up photograph of the eye of a baby with reflection of the scene in the pupil” Basile Morin / CC BY-SA 4.0 (cropped)
- Related lab (Urology Lab): “New Da Vinci Xi” Alvarogarciamd / CC BY-SA 4.0 (cropped)
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