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Biological Information Analysis (Institute of Development, Aging and Cancer) Lab
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The lab seeks to understand complex biological phenomena by analyzing large-scale data.
AboutAbout the lab
Understanding complex biological phenomena, centered on biointeraction
The Biological Information Analysis field is a lab that aims to understand complex biological phenomena by analyzing large-scale data.
The lab handles everything in an integrated way, from experimental design through large-scale measurement to data analysis, and combines experiments, multi-omics, and computational science to approach the principles of biological regulation.
It works on host dysfunction caused by cancer, the effects of daily stress on disease and aging, and the effects of using robots, avatars, and devices on the body.
The lab is located at the Institute of Development, Aging and Cancer, Tohoku University, and also has a research team at the Institute for Life and Medical Sciences, Kyoto University.
Key terms
- Multi-omics
- Analysis that examines information on different types of molecules together, such as gene sequences and expression, and metabolite levels.
- Host
- Here, the individual that carries the cancer. The focus is on the changes that occur in the body, not on the cancer cells themselves.
- Enhancer
- A region of DNA that determines when, where, and how much a gene is expressed.
ResearchResearch themes
The lab shares a common policy of understanding changes that occur in living organisms by making effective use of large-scale data. While it has become easier to measure things such as whole-genome sequences, gene expression, and metabolite levels, interpreting the data obtained and linking data across different layers remain difficult, and the lab works on these challenges.
*Illustrative imageMechanisms of cancer-induced dysfunction
The lab seeks to clarify what kinds of dysfunction cancer causes in the host's body, that is, the pathophysiological mechanisms involved. In the future, it aims to find new ways to suppress the host's pathophysiology.
*Illustrative imageMinor stress, disease, and aging
The lab thinks that small everyday disturbances gradually affect the body and may cause disease or accelerate aging. Using its own original approaches to apply minor stress, it examines the medium- to long-term effects.
*Illustrative imageEnhancer genetics
Enhancer is a collective term for non-coding DNA regions that determine when, where, and how much a gene is expressed. The goal is to clarify their functions in the living body and to make it possible to design gene expression regulation artificially.
*Illustrative imageEffects of using robots and devices on the body
During the COVID-19 pandemic, remote meeting systems became commonplace, and the use of robots and avatars has also increased. The lab uses biological information analysis to investigate what changes occur in the body when people use devices such as games, robots, and avatars.
MembersFaculty
The members of the Biological Information Analysis field include a Professor, Assistant Professors, research fellows of the field, doctoral, master's, and undergraduate students, visiting students, administrative assistants, and technical assistants.As of 2026
- ProfessorShinpei Kawaoka
- Assistant ProfessorMayuko Yoda
- Assistant ProfessorJianing Zhang
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Revolocity DNA sequencer” Scotted400 / CC BY 4.0 (cropped)
- Mechanisms of cancer-induced dysfunction: “Fluorescence microscopy of the oral cancer cells” Korinna / CC BY 4.0 (cropped)
- Minor stress, disease, and aging: “Sleep deprived” Psych 125 / CC BY-SA 3.0 (cropped)
- Enhancer genetics: “DNA double helix 45” Jerome Walker,Dennis Myts / Public domain (cropped)
- Effects of using robots and devices on the body: “NASA astronaut Jessica Meir wears a set of virtual reality goggles for a vision test (iss075e0000195)” NASA Johnson Space Center / Public domain (cropped)
- Related lab (Pediatric Pathophysiology Lab): “Visit of Stella Kyriakides, European Commissioner, to the Bambino Gesù Children's Hospital - 2024” Elisabetta Villa / European Union, 2024 / EC - Audiovisual Service / CC BY 4.0 (cropped)
- Related lab (Emergent Medicine Lab (SiRIUS Institute of Medicine)): “Barbara McClintock ( ) shown in her laboratory in 1947” Smithsonian Institution/Science Service; Restored by Adam Cuerden / Public domain (cropped)
- Related lab (Health Policy Lab (Tohoku Medical Megabank Organization)): “Unveiling of policy to facilitate the return of health workers who have been out of service (37)” The President's Office, Maldives / CC BY 4.0 (cropped)
- Related lab (Cardiovascular Surgery Lab): “Operating theatre” Piotr Bodzek, MD / CC BY-SA 3.0 (cropped)
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