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Advanced Neurosurgical Therapeutics Lab (Kohnankai Kohnan Hospital)
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A lab that studies diseases of the blood vessels in the brain, starting from surgical treatment.

AboutAbout the lab
Exploring cerebrovascular disease through surgical treatment
The Advanced Neurosurgical Therapeutics Lab studies diseases of the blood vessels in the brain, using surgical treatment of cerebrovascular disorders as its starting point.
Its targets include cerebral aneurysms, moyamoya disease, and cerebrovascular malformations, and it works on developing new treatments, studying disease mechanisms, and investigating cerebral circulation and metabolism.
It is a department of the Graduate School of Medicine, Department of Medical Science, and its name includes Kohnankai Kohnan Hospital.
Key terms
- Moyamoya disease
- A disease of the blood vessels in the brain. It has been increasing in recent years as a cause of stroke in young people.
- Perioperative period
- The period around surgery, including before and after the operation. This lab studies the pathophysiology during the perioperative period of bypass surgery.
- Aneurysm wall imaging
- A method that uses high-sensitivity MRI to image the vessel wall of a cerebral aneurysm. In English it is called vessel wall imaging.
ResearchResearch themes
Using surgical treatment of cerebrovascular disorders as its starting point, the lab develops new treatments for cerebral aneurysms, moyamoya disease, and cerebrovascular malformations, studies disease mechanisms, and investigates cerebral circulation and metabolism. It also studies dissecting aneurysms and cerebrovascular malformations from both clinical and basic research perspectives.
*Illustrative imagePathophysiology of moyamoya disease and bypass surgery
The lab studies moyamoya disease, which has been increasing in recent years as a cause of stroke in young people, drawing on more than half a century of clinical experience. The work centers on genetic research and on clarifying the pathophysiology during the perioperative period of bypass surgery.
*Illustrative imageMechanisms of cerebral aneurysm growth and rupture
The lab investigates how cerebral aneurysms, which cause subarachnoid hemorrhage, grow and rupture. It uses high-sensitivity MRI for aneurysm wall imaging and computational fluid dynamics analysis.
MembersFaculty
- ProfessorShunsuke Omodaka
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images.
- Top image: “Cerebral angiography, arteria vertebralis sinister injection” Lipothymia / Public domain (cropped)
- Pathophysiology of moyamoya disease and bypass surgery: “St John of God Midland Private Hospital, August 2026 05” Samuel Wiki / CC0 (cropped)
- Mechanisms of cerebral aneurysm growth and rupture: “MRI-Philips” Jan Ainali / CC BY 3.0 (cropped)
- Related lab (Neurosurgery Lab): “Operating-room 1” 연세건우병원 / CC BY 4.0 (cropped)
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- Related lab (Cyclotron Nuclear Medicine Lab (Center for Advanced Quantum Beam Science)): “PET recortada” Muchay Fotografía tomada por este usuario durante el evento / CC0 (cropped)
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