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Pharmacology Lab
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A pharmacology lab that works on drug nurturing and drug discovery, starting from the links between bones and joints and nerves and blood vessels.
AboutAbout the lab
Broadcast a paradigm shift!
The Pharmacology Lab conducts research on drug nurturing and drug discovery, targeting bones and joints and the nerves and blood vessels associated with them.
It pursues clinically relevant research on metabolic bone diseases such as osteoporosis, joint diseases such as osteoarthritis and rheumatoid arthritis, and skeletal pain including orofacial pain.
By comparing the bones of the jaw and mouth with those of the trunk and limbs, the lab explores how drugs act and how diseases arise.
It incorporates molecular omics and imaging to analyze from the molecular level to the whole organism in an integrated way.
Key terms
- Metabolic bone disease
- A disease caused by an imbalance between bone formation and bone breakdown. Osteoporosis is one example
- Drug nurturing (ikuyaku)
- Research that examines the efficacy and use of drugs already in use, and develops them into better drugs
- Imaging
- Methods of studying the shape and movement of cells and tissues by making them visible with microscopes or imaging devices
NewsLab news
Assistant Professor Tsuji received the Excellent Presentation Award from the Hokkaido Drug Action Discussion Meeting
A review article with Assistant Professor Nakanishi as first author was published in J Oral Biosci
An original paper with Assistant Professor Tsuji as corresponding author was published in Regen Ther
A graduate student received the Young Investigator Award from the Japanese Society for Bone Morphometry
Assistant Professor Nakanishi received The Francesca Miotti Award at the European Orthodontic Society Congress
ResearchResearch themes
The lab conducts research on drug nurturing and drug discovery, with an emphasis on the links between the musculoskeletal system (bone, cartilage, joints, etc.) and nerves and blood vessels. Its work includes the effects of drugs that improve bone metabolism and of antiviral drugs on the musculoskeletal system, developing methods to evaluate drug efficacy using biomarkers and imaging, the interplay between osteoblasts and osteoclasts, and the effects of mechanical force on cells of bone and periodontal tissue.
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MembersFaculty
The members of the Pharmacology Lab consist of faculty and graduate students (including graduate students affiliated with other labs).As of 2026
- ProfessorTadahiro Iimura
- Associate ProfessorYoshitaka Yoshimura
- Assistant ProfessorNaoki Tsuji
- Assistant ProfessorNoriko Nakanishi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Spongy bone - Trabecular bone -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Comparing Jaw and Whole-Body Bone through Pharmacology: “Base of mandible - skull - lateral view01” BodyParts3D/Anatomography / CC BY-SA 2.1 jp (cropped)
- Related lab (口腔診断内科学教室): “Dentist Examining Patient’s Teeth with Dental Mirror” Jameswasswa / CC BY-SA 4.0 (cropped)
- Related lab (生化学教室): “Rheumatology - Osteoporotic bone -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Related lab (硬組織微細構造学教室): “Bone histomorphometry” Jbakalovic / CC BY 4.0 (cropped)
- Related lab (口腔機能解剖学教室): “Gl.submandibularis” Rollroboter / CC BY-SA 4.0 (cropped)
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