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Periodontology Lab
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A periodontology lab that studies the regeneration of lost periodontal tissue and the links between periodontal disease and the rest of the body.
AboutAbout the lab
Getting lost periodontal tissue back.
The Periodontology Lab conducts a broad range of research on periodontal disease, from basic to clinical studies.
The lab works on regenerating lost periodontal tissue using growth factors and scaffolds, which are materials that serve as a foothold for cells.
It also investigates the mechanisms linking the mouth and the whole body, such as how periodontal disease affects digestive and respiratory diseases.
The lab values the independence of graduate students and supports them in taking on new research that goes beyond the lab's existing themes.
Key terms
- Periodontal tissue
- The tissues around a tooth that support it, including the gums, the periodontal ligament, and the supporting bone
- Growth factor
- A protein that promotes the growth of cells or their differentiation into specific cell types
- Scaffold
- A material that serves as a foothold where cells can settle and multiply when tissue is being regenerated
NewsLab news
Paper by Prof. Takahashi and colleagues published in Clinical Oral Investigations
Prof. Takahashi received the Japanese Society of Periodontology Encouragement Award
Paper by Project Professor Sugaya and colleagues published in the Japanese Journal of Conservative Dentistry
Prof. Takahashi received the Excellent Presentation Award in Periodontal Tissue Regenerative Medicine (Japanese Society of Periodontology)
ResearchResearch themes
The lab conducts a broad range of research on periodontal disease, from basic to clinical studies. Its two main pillars are the regeneration of lost periodontal tissue and the mechanisms by which periodontal disease affects the whole body.
*Illustrative imageRegeneration of Lost Periodontal Tissue
The lab evaluates the regenerative capacity of new scaffolds that incorporate growth factors such as bFGF and BMP, using cell experiments and bone defect models in rats and dogs. It also investigates a regeneration method that uses very weak high-frequency current in animal experiments.
*Illustrative imagePeriodontal Disease and Systemic Disease
Using periodontitis model mice and other models, the lab seeks to clarify how periodontal disease affects digestive and respiratory diseases, and the molecular mechanisms involved.
*Illustrative imageGingival Barrier and Control of Inflammation
The lab focuses on how gingival epithelial cells, which make up periodontal tissue, regulate barrier function, and on how immune cells suppress inflammation. It aims to apply this knowledge to the prevention and treatment of periodontal disease.
MembersFaculty
The members of the Periodontology Lab are faculty, clinical staff, graduate students, academic researchers, resident dentists, and visiting clinical dentists. A Project Professor from an endowed department also takes part.As of 2025
- ProfessorNaoki Takahashi
- LecturerShinji Shimoji
- Assistant ProfessorTomoomi Odajima
- Assistant ProfessorAkihito Kato
- Assistant ProfessorMegumi Nakatsuka
- Assistant ProfessorHiroe Fukuda
- Assistant ProfessorTaro Washizu
- Project ProfessorTsutomu Sugaya
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dental explorer and periodontal probe” Coronation Dental Specialty Group / CC BY-SA 3.0 (cropped)
- Regeneration of Lost Periodontal Tissue: “Binder CB 210 incubator interior” Shinryuu / Public domain (cropped)
- Periodontal Disease and Systemic Disease: “CSIRO ScienceImage 3567 Examining an agar dish for bacterial colonies as part of the bioremediation project” David McClenaghan, CSIRO / CC BY 3.0 (cropped)
- Gingival Barrier and Control of Inflammation: “Epithelial Tissues Stratified Squamous Epithelium ( )” Berkshire Community College Bioscience Image Library / CC0 (cropped)
- Related lab (Biochemistry Lab): “Rheumatology - Osteoporotic bone -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Related lab (Restorative Dentistry Lab): “Composite resin fillng 3” Albert / CC BY-SA 3.0 (cropped)
- Related lab (Comprehensive Dental Care Lab): “LightScalpel Dental CO2 Laser” Academicguru22 / CC BY-SA 4.0 (cropped)
- Related lab (Oral Functional Anatomy Lab): “Gl.submandibularis” Rollroboter / CC BY-SA 4.0 (cropped)
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