LAB LOGA page on LabLog, a review site (not the lab's official page)
Genome Medical Biology Lab
Machine-translated · View original
The lab investigates the three-dimensional structures that the genome forms inside the nucleus and the roles they play.
AboutAbout the lab
Reading life phenomena through the three-dimensional structure of the genome
The Genome Medical Biology Lab studies the three-dimensional structures that the genome forms inside the nucleus, and the roles those structures play in biological phenomena.
Genome structure is closely linked to transcription and to DNA replication and repair, and its disruption is known to be involved in cancer and developmental disorders.
Using cultured human cells and fission yeast, the lab combines genomics based on next-generation sequencing with genetics, cell biology, and biochemistry.
Professor Noma is a cross-appointed professor who runs labs at both Hokkaido University and the University of Oregon in the United States, and responds to students while staying in constant contact with Associate Professor Ohta.
Key terms
- Genome
- The entirety of an organism's genetic information, written as the base sequence of DNA
- Fission yeast
- A yeast that multiplies by splitting its cell in two. It is one of the model organisms that are easy to use in experiments
- Condensin
- A protein complex that contains SMC proteins. It is known to condense chromosomes during cell division (M phase)
- Cellular senescence
- A state in which cells, after being exposed to stress or similar insults, stop dividing and remain stably arrested in growth
NewsLab news
A paper by a doctoral student was accepted by the Journal of Investigative Dermatology
A paper by a doctoral student was published in the Journal of Biochemistry
ResearchResearch themes
In eukaryotes, the genome exists inside the nucleus as an ordered structure. The lab aims to elucidate the molecular mechanisms that determine genome structure and the roles that structure plays in nuclear processes such as transcription.
*Illustrative imageCondensin, cohesin, and genome structure
The lab studies how condensin and cohesin, SMC protein complexes at the center of chromosome dynamics, build defined genome structures, and the roles those structures play in nuclear processes such as transcription.
*Illustrative imageCellular senescence and genome structure
Focusing on two types of cellular senescence, oncogene-induced senescence and replicative senescence, the lab aims to elucidate the genome structures that condensin forms in senescent cells and the mechanism that activates transcription of senescence genes.
*Illustrative imageOrganization of genome structure in fission yeast
Using genomics methods such as ChIA-PET and in situ Hi-C in fission yeast, the lab examines interactions between genomic regions and investigates how condensin builds genome structure through its binding to transcription factors.
MembersFaculty
The members of the Genome Medical Biology Lab consist of faculty, secretaries, technical assistants, postdocs, doctoral students, and medical students.As of 2026
- ProfessorKenichi Noma
- Associate ProfessorShinya Ohta
- Associate ProfessorHideki Tanizawa
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Genome Medical Biology Lab
RNA Biology LabSchool of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyLife science from the perspective of RNA biology (noncoding …
Molecular Cell Biology LabSchool of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyCell fate determination by intracellular protein carboxylati…
Bioanalytical Chemistry LabSchool of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyAnalysis of pathology and biological function by biomolecula…
Natural Products Chemistry LabSchool of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of PharmacyApplication of natural bioactive substances to life sciencesThe information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Condensation1” Ascendinglotus2 / CC BY-SA 3.0 (cropped)
- Condensin, cohesin, and genome structure: “Three Condensins” Ascendinglotus2 / CC BY-SA 3.0 (cropped)
- Cellular senescence and genome structure: “SABG MEFs” Y tambe / CC BY-SA 3.0 (cropped)
- Organization of genome structure in fission yeast: “Fission yeast division” G Lens Microscopist, Liam Pennington / CC BY 4.0 (cropped)
- Related lab (RNA生物学研究室): “FISH 13 21” Gregor1976 / Public domain (cropped)
- Related lab (遺伝子病制御研究所 フロンティア研究ユニット 分子細胞生物研究室): “Vesicular Stomatitis Virus (VSV) particles (orange) found in extracellular space and budding from the plasma membrane of infected cells (teal)” NIAID / CC BY 2.0 (cropped)
- Related lab (生体分析化学研究室): “Molecubes SPECT uCT and PET” Adville / CC BY-SA 4.0 (cropped)
- Related lab (天然物化学研究室): “Esponja (Theonella swinhoei), Anilao, Filipinas, , DD 67” Diego Delso / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.