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Laboratory Animal Science Lab
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The lab studies laboratory animal science, using animals such as mice and rats to understand how diseases develop.
AboutAbout the lab
Balancing advances in life science with animal welfare
The Laboratory Animal Science Lab uses laboratory animals such as mice and rats to study the mechanisms of diseases, including genetic disorders and infectious diseases.
The lab also takes on the challenge of developing new disease models using new animal species such as cotton rats and genetically modified animals.
From a veterinary medicine standpoint, the lab also works on the health and welfare of laboratory animals.
The lab also carries out activities that contribute to training board-certified specialists in laboratory animal medicine.
Key terms
- Strain
- A group of laboratory animals maintained by breeding over generations so that their genetic characteristics remain uniform
- Disease model animal
- An animal that shows symptoms similar to a disease of humans or animals and is used to study the mechanisms and treatments of that disease
- Genetically modified mouse
- A mouse in which a specific gene has been disrupted or added so that the function of that gene can be studied
ResearchResearch themes
Using laboratory animals such as mice and rats, the lab aims to elucidate and overcome the mechanisms of diseases such as genetic disorders and infectious diseases. It also works on developing new models using new animal species such as cotton rats and genetically modified animals.
*Illustrative imageStrain differences in susceptibility to infectious diseases
When two mouse strains (B6 and D2) are compared, B6 mice show milder symptoms and D2 mice show more severe symptoms in Sendai virus infection, Mycoplasma pneumonia, and echinococcosis alike. The lab aims to identify which genes determine this difference.
*Illustrative imageAnimal models of disease through genetic modification
The lab creates and analyzes genetically modified mice to clarify the detailed mechanisms of cancer and inflammatory diseases, with the aim of contributing to the development of new preventive methods and treatments.
MembersFaculty
The members of the Laboratory Animal Science Lab are faculty and graduate and undergraduate students.As of 2026
- ProfessorMasami Morimatsu
- Associate ProfessorTeppei Nakamura
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Hispid cotton rat (Sigmodon hispidus) - National Butterfly Center - Mission - Texas - USA” Chuck Homler d/b/a Focus On Wildlife / CC BY-SA 4.0 (cropped)
- Strain differences in susceptibility to infectious diseases: “House mouse (Mus musculus) 2732” Ahunt / CC0 (cropped)
- Animal models of disease through genetic modification: “20251019 Replica DNA double helix model Berlin 01” Flocci Nivis / CC BY 4.0 (cropped)
- Related lab (寄生虫学教室): “Ezo Red Fox (Vulpes vulpes schrencki), 2024” MIKI Yoshihito / CC BY 2.0 (cropped)
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- Related lab (比較病理学教室): “Tissue processing - Stained and mounted slides in the ubiquitous 20-slide folder” Ed Uthman / CC BY-SA 2.0 (cropped)
- Related lab (先端獣医療学教室
（附 属動物病院） ): “Camp Lemonnier Service members Perform Surgery on Hektor, a Djiboutian K-9 Working Dog DVIDS217501” Master Sgt. Carlotta Holley / Public domain (cropped)
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