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Veterinary Internal Medicine Lab
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A veterinary internal medicine lab that uncovers the causes of dog and cat diseases from the clinical setting.
AboutAbout the lab
Cross-talk between clinical practice and research
The Veterinary Internal Medicine Lab treats sick animals brought to the Hokkaido University Veterinary Teaching Hospital while also researching their diseases.
Its motto is to find research themes in daily clinical practice and return the results to clinical care.
Under the shared goals of improving diagnostic accuracy, elucidating disease mechanisms, and developing novel treatments, the lab works on diagnostic imaging such as ultrasound, CT, MRI, and endoscopy, as well as analysis of how diseases develop.
After being assigned to the lab, undergraduate students also take part in internal medicine clinical work under the supervision of veterinarians and carry out their graduation research alongside clinical practice.
Key terms
- Elucidation of disease mechanisms
- Clarifying the mechanisms by which a disease arises and progresses.
- Elastography
- An examination technique that uses ultrasound to represent the stiffness of body tissue as images or numerical values.
- Transcranial Doppler ultrasonography
- An examination that applies ultrasound from outside the head to measure the speed of blood flowing through the blood vessels of the brain.
NewsLab news
A doctoral student received the Clinical Research Award at the Scientific Meeting of the Japan Academy of Veterinary Internal Medicine
A doctoral student received the Excellent Presentation Award at the Regular Meeting of the Japanese Society of Veterinary Cardiology
A doctoral student received the Excellent Presentation Award (Clinical Division) at the Scientific Meeting of the Japanese Society of Veterinary Science
A doctoral student received the Best Research Presentation Award at the Regular Meeting of the Japanese Society of Veterinary Cardiology
A doctoral student received the Hokkaido Veterinary Medical Association President's Award at the Japanese Society of Small Animal Veterinary Medicine (Hokkaido)
ResearchResearch themes
Guided by the principle of cross-talk between clinical practice and research, the lab addresses themes found in the clinic through clinical studies and basic preclinical studies. Research is carried out by three units: gastrointestinal, hepatic, and neurological.
*Illustrative imageColorectal polyps in Dachshunds
The lab studies inflammatory colorectal polyps, which are common in Miniature Dachshunds. By comprehensively analyzing genes to find those associated with susceptibility to the disease, it aims to clarify the mechanisms of onset and malignant transformation.
*Illustrative imageMeasuring liver stiffness with ultrasound
The lab is developing a method, shear wave elastography, to measure liver stiffness objectively and numerically with ultrasound, without surgery, and is working to make it usable in veterinary practice.
*Illustrative imageDetecting seizures through cerebral blood flow
Using transcranial Doppler ultrasonography, which examines cerebral blood flow from outside the head, the lab studies noninvasive methods for diagnosing brain diseases and for detecting epileptic seizures that are not accompanied by convulsions.
MembersFaculty
Members of the Veterinary Internal Medicine Lab consist of faculty and administrative assistants.As of 2026
- ProfessorMitsuyoshi Takiguchi
- Associate ProfessorKensuke Nakamura
- Assistant ProfessorNozomu Yokoyama
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “US, Ghana medical staff participate in medical exercise (8439610)” U.S. Army photo by Cpl. Clara Soria / Public domain (cropped)
- Colorectal polyps in Dachshunds: “MiniDachshundLongCoatGold” Tryso2000 / CC BY-SA 4.0 (cropped)
- Measuring liver stiffness with ultrasound: “Transient Elastography (Fibroscan) of the Liver” Goleisureintl / CC BY-SA 4.0 (cropped)
- Detecting seizures through cerebral blood flow: “Transcranial doppler” Runeaaslid at English Wikipedia / CC BY 3.0 (cropped)
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