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Applied Molecular Entomology Lab
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This lab studies, at the molecular level, the viruses and bacteria that cause disease in insects.
AboutAbout the lab
Uncovering the mechanisms of insect pathogens at the molecular level
The Applied Molecular Entomology Lab studies, at the molecular level, how viruses and bacteria cause disease in insects.
The lab works on developing technologies that make use of the way viruses take over insect cells, and on clarifying how insecticidal proteins produced by bacteria work.
From June to October is the silkworm rearing season, and during this period students sometimes also work on the farm.
The lab holds a weekly lab seminar for introducing papers, as well as a research progress meeting.
Key terms
- Gene expression
- The process by which proteins and other products are made based on the information in genes. When and how much is produced is finely regulated
- Viral vector
- A "carrier" that uses the properties of a virus to deliver a gene of interest into cells. It is used for purposes such as protein production
- Insecticidal protein
- A protein produced by some bacteria that acts as a poison only against specific insects
ResearchResearch themes
The lab clarifies, at the molecular level, how viruses and bacteria that cause disease in insects infect and act on their hosts. It aims to use these mechanisms to establish technologies that benefit society, such as producing useful substances and managing pests.
*Illustrative imageHow viruses take over insect cells
The lab investigates how gene expression of insect viruses is regulated, using whole insects, insect cells, and mammalian cells. It also works on building production systems for useful substances using viral vectors, and on creating virus-resistant silkworms through genetic modification.
*Illustrative imageHow insect-pathogenic bacteria kill insects
Focusing on Bacillus thuringiensis, a bacterium that causes disease in insects, the lab searches for the insecticidal proteins it produces and clarifies how they work. It aims to propose pest management approaches that use this bacterium.
MembersFaculty
- ProfessorShinichiro Asano
- Associate ProfessorMasanao Sato
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Da Lat - Silkworms eating mulberry leaves” P. Hughes / CC BY 4.0 (cropped)
- How viruses take over insect cells: “4thInstarLarvae3500px” FASTILY (TALK) / CC BY-SA 3.0 (cropped)
- How insect-pathogenic bacteria kill insects: “Bt-toxin-crystals” Jim Buckman is credited and the original uploader is P.R.Johnston. / Public domain (cropped)
- Related lab (Molecular Biology Lab): “Arabidopsis thal twice background” Reo On / CC BY-SA 3.0 (cropped)
- Related lab (Genome Biochemistry Lab): “Sirex noctilio emerging” Paula Klasmer, Instituto Nacional de Tecnologia Agropecuaria, Argentina / CC BY 3.0 (cropped)
- Related lab (Molecular Enzymology Lab): “Potato amyloplast granules observed at 200 magnification under a polarized microscope with interference plate inserted. Massimo Brizzi 2021” Massimo Brizzi / CC BY 4.0 (cropped)
- Related lab (Gene Regulation Lab): “Sugar beet field ( )” Gilles San Martin from Namur, Belgium / CC BY-SA 2.0 (cropped)
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