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Gene Regulation Lab
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This lab uses sugar beet and spinach to probe the mysteries of plant reproduction and the genome.

AboutAbout the lab
Uncovering the mechanisms of plant reproduction from the level of genes
The Gene Regulation Lab uses sugar beet and spinach to study plant reproduction and the structure, expression, and evolution of the genome.
Its main theme is how plant traits, especially those related to reproduction, are regulated.
The lab uncovers these mechanisms using methods from genetics, molecular biology, and biochemistry, and considers their biological significance by adding data on diversity and evolution.
Key terms
- Cytoplasmic male sterility
- A trait in which pollen is no longer produced, caused by the combination of mitochondrial and nuclear genes. It is also used in breeding new varieties
- Dioecy
- A condition in which a plant species has separate individuals that bear only male flowers and individuals that bear only female flowers. Spinach is a representative example
- Hybrid seed
- Seed produced by crossing parents with different traits. The offspring often grow better than their parents, and hybrid seed is widely used for vegetables and other crops
ResearchResearch themes
The lab's research starts from the view that genetic improvement of plants requires understanding how genetic information in the nucleus, chloroplasts, and mitochondria is organized and expressed. Its main theme is the regulation of the expression of plant traits, especially those related to reproduction.
*Illustrative imageThe mechanism behind the inability to produce pollen
Cytoplasmic male sterility, in which pollen is no longer produced, arises from the interaction between genes in the cytoplasm (mitochondria) and the nucleus. The lab is working to clarify this mechanism, aiming for an understanding that spans population genetics, ecology, and plant breeding.
*Illustrative imageSex determination and sex chromosomes in spinach
In spinach, a representative dioecious crop, the lab studies how male and female plants are determined and how sex chromosomes arose. It aims to apply this knowledge to the production of hybrid seed in crops.
MembersFaculty
The lab's members are faculty, research assistants, and doctoral, master's, and undergraduate students.As of 2022
- ProfessorTomohiko Kubo
- Associate ProfessorYasuyuki Onodera
- LecturerKazuyoshi Kitazaki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Sugar beet field ( )” Gilles San Martin from Namur, Belgium / CC BY-SA 2.0 (cropped)
- The mechanism behind the inability to produce pollen: “Beta vulgaris sl2” Stefan.lefnaer / CC BY-SA 4.0 (cropped)
- Sex determination and sex chromosomes in spinach: “Spinacia oleracea male flowers, spinazie mannelijke bloemen” Rasbak / CC BY-SA 3.0 (cropped)
- Related lab (Molecular Biology Lab): “Arabidopsis thal twice background” Reo On / CC BY-SA 3.0 (cropped)
- Related lab (Genome Biochemistry Lab): “Sirex noctilio emerging” Paula Klasmer, Instituto Nacional de Tecnologia Agropecuaria, Argentina / CC BY 3.0 (cropped)
- Related lab (Molecular Enzymology Lab): “Potato amyloplast granules observed at 200 magnification under a polarized microscope with interference plate inserted. Massimo Brizzi 2021” Massimo Brizzi / CC BY 4.0 (cropped)
- Related lab (Applied Molecular Entomology Lab): “Da Lat - Silkworms eating mulberry leaves” P. Hughes / CC BY 4.0 (cropped)
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