LAB LOGA page on LabLog, a review site (not the lab's official page)
Kimura-Fujimori Lab
Machine-translated · View original
The lab explores how sperm and eggs are formed by studying how the genome functions.
AboutAbout the lab
Understanding the functions of the mammalian genome
The Kimura-Fujimori Lab studies the functions of the mammalian genome, especially how gene expression is regulated.
Using mouse testis, ovary, and placenta, the lab investigates how genes are activated when sperm and eggs are formed.
The key players are long noncoding RNAs, which function without being made into proteins, and DNA sequences that serve two roles.
When necessary, the lab generates transgenic mice to confirm the functions of genes.
Key terms
- Long noncoding RNA
- An RNA of 200 or more nucleotides that functions without being translated into protein. It has diverse roles in the nucleus and cytoplasm.
- Transcription
- The process in which a gene on DNA is copied into mRNA. The mRNA is then translated into protein.
- Granulosa cells
- Cells that surround the egg in the ovary. They produce hormones in response to hormones from the pituitary gland and support the maturation of the egg.
NewsLab news
Published a paper on long noncoding RNAs in the testis in Reproductive Sciences
Published a paper on the PRSS locus in the human testis in Molecular Reproduction and Development
A master's student received the Best Presentation Award at the master's thesis presentation
A paper co-authored by Assistant Professor Fujimori at a previous lab was published in Science
ResearchResearch themes
The lab aims to clarify the functions of sequences that do not code for proteins, which make up most of the genome. In particular, it studies how gene expression is regulated in the ovary, testis, and placenta, the organs responsible for reproduction and development.
*Illustrative imageTranscriptional activation in spermatogenesis
In the testis, many important genes are activated during meiosis. Focusing mainly on primary spermatocytes, the lab investigates the mechanisms behind this activation, paying particular attention to DNA sequences that function as both promoters and enhancers, and to long noncoding RNAs.
*Illustrative imageTranscriptional activation in ovarian granulosa cells
Granulosa cells, which surround the egg, respond to hormones and also produce hormones themselves. Using the POP and Amhr2 genes, which are highly active in these cells, as examples, the lab investigates how transcription is activated.
*Illustrative imageFunctions of proteases
Among proteases, the enzymes that break down proteins, the lab analyzes the Prss/Tessp genes, which are involved in spermatogenesis, and the function of POP, which is involved in placental differentiation. Both are areas where research has made little progress.
MembersFaculty
The Kimura-Fujimori Lab consists of faculty members and doctoral, master's, and undergraduate students.As of 2026
- ProfessorAtsushi Kimura
- Assistant ProfessorChika Fujimori
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Kimura-Fujimori Lab
Reproductive and Developmental Biology Lab, Ogiwara GroupFaculty of Science, Department of Biological SciencesReproductive biology
Katsu LabFaculty of Science, Department of Biological SciencesComparative endocrinology
Hayakawa LabFaculty of Science, Department of Biological SciencesGenome science, molecular ecology, and evolutionary biology
Environmental Molecular Biology LabFaculty of Science, Department of Biological SciencesEnvironmental biology, molecular biologyThe information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Black-mouse-trio-in-cage-2” Commissioned by Understanding Animal Research / CC BY-SA 4.0 (cropped)
- Transcriptional activation in spermatogenesis: “3D-SIM-2 Nucleus prophase 3d rotated” Lothar Schermelleh / CC BY-SA 3.0 (cropped)
- Transcriptional activation in ovarian granulosa cells: “Ovarian cortex in a rhesus monkey” Tulemo / CC BY-SA 4.0 (cropped)
- Functions of proteases: “Protein F11 PDB 1xx9” Emw / CC BY-SA 3.0 (cropped)
- Related lab (Reproductive and Developmental Biology Lab, Ogiwara Group): “Oryzias latipes(Hamamatsu,Shizuoka,Japan,2007)-1” Seotaro / CC BY-SA 3.0 (cropped)
- Related lab (Katsu Lab): “Callorhinchus milii Sunshine” Totti / CC BY-SA 4.0 (cropped)
- Related lab (Hayakawa Lab): “013 Alpha male chimpanzee at Kibale forest National Park Photo by Giles Laurent” Giles Laurent / CC BY-SA 4.0 (cropped)
- Related lab (Environmental Molecular Biology Lab): “Reissetzlinge vor der Aussaat” Myrmux / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.