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Katsu Lab
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The lab traces how receptors for sex hormones arose over the course of evolution.
AboutAbout the lab
Unraveling the mysteries of life through nuclear receptors
The Katsu Lab studies how the proteins that receive sex hormones (receptors) arose during evolution.
The lab isolates receptor genes from animals at key points in animal evolution, such as cartilaginous fishes, ancient fishes, lampreys, and amphioxus, and examines their functions.
It traces when and how the precise endocrine systems of higher vertebrates came into being.
Key terms
- nuclear receptor
- A protein that, when bound by a hormone or similar molecule, regulates gene expression inside the cell nucleus.
- steroid hormones
- A group of fat-soluble hormones such as estrogens and androgens. They act in the development and differentiation of reproductive organs.
- endocrine system
- A mechanism of the body in which hormones are released into the blood to regulate the function of distant organs.
NewsLab news
Paper on TRP in the elephant shark published
Paper on the mineralocorticoid receptor of apes published
Paper on the mineralocorticoid receptor published
ResearchResearch themes
Focusing on steroid hormone receptors, the lab studies their molecular evolution and functional evolution. It isolates receptor genes from various organisms and analyzes their functions to explore how endocrine systems came to be.
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MembersFaculty
The Katsu Lab consists of faculty members, graduate students, and undergraduate students.
- ProfessorYoshinao Katsu
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Callorhinchus milii Sunshine” Totti / CC BY-SA 4.0 (cropped)
- Molecular Evolution of Receptors: “Branchiostoma lanceolatum” Hans Hillewaert / CC BY-SA 4.0 (cropped)
- Related lab (Kimura-Fujimori Lab): “Black-mouse-trio-in-cage-2” Commissioned by Understanding Animal Research / CC BY-SA 4.0 (cropped)
- Related lab (Soma Lab): “Java Sparrow. (Lonchura oryzivora), ( )” Bernard Spragg. NZ from Christchurch, New Zealand / CC0 (cropped)
- Related lab (Diversity Biology Ia Lab): “Micrura verrilli” Marlin Harms / CC BY 2.0 (cropped)
- Related lab (Hokkaido University Field Ornithology Lab): “Otus elegans from iNaturalist photo” WeitingLiu (weitingliu) / CC BY 4.0 (cropped)
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