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Veterinary Reproduction and Breeding Lab
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A lab that uses hormones as a clue to explore the mechanisms of sex and reproduction in animals.
AboutAbout the lab
From cutting-edge basic research to applied research that promotes the livestock industry.
The Veterinary Reproduction and Breeding Lab studies the mechanisms of sex and reproduction in mammals, with "hormones" as its keyword.
The lab aims to put its findings to use in livestock production settings.
Its goals are both to breed livestock efficiently and to reduce the numbers of wild animals that damage crops.
The lab also hosts a research group in farm animal clinical medicine.
Key terms
- Kisspeptin neuron
- A nerve cell in the hypothalamus of the brain. It sits at the top of the system that commands the secretion of reproductive hormones.
- Cell line
- Cells taken from the body and made so that they can be cultured and propagated continuously.
- Follicle
- A sac-like structure in the ovary that encloses and nurtures the egg. Once it has matured sufficiently, ovulation occurs.
- Endometritis
- Inflammation of the uterus caused by bacterial infection. It is one of the major causes of reproductive disorders in dairy cows after calving.
NewsLab news
Professor Matsuda received the FY2025 Japanese Society of Animal Reproduction Society Award (Academic Award)
A paper by a doctoral student received the Excellent Paper Award from the Japanese Society of Farm Animal Clinical Medicine
A student received an Outstanding Presentation Award at the 167th Scientific Meeting of the Japanese Society of Veterinary Science
A doctoral student received an Outstanding Presentation Award at the 117th Annual Meeting of the Japanese Society of Animal Reproduction
ResearchResearch themes
Using "hormones" as its keyword, the lab clarifies the mechanisms of sex and reproduction in mammals and aims to apply them in the field. Centered on how the brain controls reproduction, it studies ovulation, reproductive disorders in dairy cows, and technology for in vitro fertilized embryos.
*Illustrative imageHow the brain controls reproduction
The lab investigates how kisspeptin neurons, the brain cells that control reproduction, are regulated, using goats and rats. It has also established a cell line of goat hypothalamic neurons and uses it in its research.
*Illustrative imageApplying brain mechanisms to reproductive control
Drawing on knowledge of how the brain works, the lab aims to develop drugs that promote reproduction in livestock, as well as drugs that suppress reproduction in order to manage populations of wild animals and zoo animals.
*Illustrative imageHow the number of ovulations is determined
The number of follicles that grow to the point of ovulation is fixed for each animal species. Using analysis of bovine ovaries and genetically modified mice, the lab searches for new factors that determine that number.
*Illustrative imageEndometritis and the ovary in dairy cows
In endometritis, which is common in dairy cows after calving, the lab examines how toxins released by bacteria affect ovarian function, through clinical studies in dairy cows and in vitro culture of follicles.
MembersFaculty
The members of the Veterinary Reproduction and Breeding Lab consist of faculty members, project researchers, academic specialist staff, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorHisashi InokumaPublications ↗
- ProfessorFuko MatsudaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cows near Kiel - Maack - July 2010” Smaack / CC BY-SA 4.0 (cropped)
- How the brain controls reproduction: “Domestic Goat Portrait (aka)” André Karwath aka Aka / CC BY-SA 2.5 (cropped)
- Applying brain mechanisms to reproductive control: “Herd of Sika deer - geograph.org.uk - 4213722” Oliver Dixon / CC BY-SA 2.0 (cropped)
- How the number of ovulations is determined: “Graafian Follicle, Human Ovary ( )” Ed Uthman / CC BY 2.0 (cropped)
- Endometritis and the ovary in dairy cows: “Milchkuh auf Weide in NRW” Angela Marie / CC BY 2.0 (cropped)
- Related lab (Veterinary Anatomy Lab): “Seminiferous tubule and sperm” Nephron / CC BY-SA 3.0 (cropped)
- Related lab (Veterinary Pharmacology Lab): “Small intestine low mag” Nephron / CC BY-SA 3.0 (cropped)
- Related lab (Food and Biological Function Models Lab): “Grazing cattle - panoramio” 伊藤善行 / CC BY-SA 3.0 (cropped)
- Related lab (Infection Control Lab): “Colorized electron micrograph of HPV virus particles (teal)” NIAID / CC BY 2.0 (cropped)
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