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Veterinary Anatomy Lab
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The lab explores how the gonads and other organs form, starting from the mystery of “form.”
AboutAbout the lab
Exploring the mysteries hidden within “form”
The Veterinary Anatomy Lab focuses on the “form” of living things and studies them from the perspective of morphology.
In particular, it investigates gonad development, cell differentiation, immunity, and evolution, focusing on the gonads that nurture the germ cells that give rise to sperm and eggs.
It uses a wide range of methods, from gross anatomy observed with the naked eye to histology, molecular biology, and the generation of knockout mice.
It is a lab where students can choose their own research topics based on their own interests.
Key terms
- Sex differentiation
- The process by which a body developing in the womb diverges to take on male or female characteristics.
- SRY
- A gene on the Y chromosome that acts as the switch for forming the testes. SOX genes are related to it.
- Biliary atresia
- A disease in which the passage for bile produced in the liver becomes blocked. It occurs in babies around the time of birth.
- Embryoid body
- A cluster of cells made from stem cells that resembles an early-stage embryo.
NewsLab news
A joint paper from the lab received the Ryotaro-chan Memorial Award (Outstanding Paper Award)
Discovery of an upstream region of a gene that is essential for maintaining SOX17 expression in the gallbladder
Chimpanzee naive iPS cells established in an international collaborative study including Institute of Science Tokyo
Development of an imaging method that uses food coloring to make the gallbladder and bile ducts easier to see
Clarification of the changes that occur in the bile ducts at the liver hilum in biliary atresia
ResearchResearch themes
The lab studies, from the perspective of morphology, how a single fertilized egg gives rise to cells of many different forms and how the animal body is built. Its main themes are gonad development and sex differentiation, the functions of SOX genes, implantation, and organogenesis.
*Illustrative imageGonad development and sex differentiation
Using mice, the lab investigates at the molecular level how the gonads, which give rise to the testes and ovaries, differentiate into male or female, and how sperm are produced.
*Illustrative imageFunctions of SOX genes
The lab studies the roles of SOX17, a member of the SRY-related gene family, in development and disease. It also works on how the gallbladder and bile ducts form and how biliary atresia arises.
*Illustrative imageHow embryos implant in the uterus
Using mouse embryos and human embryoid bodies, the lab seeks to clarify, from a morphological perspective, the initial events by which a fertilized embryo implants in the uterus.
*Illustrative imageOrganogenesis and MAB21
The lab studies the roles that members of the MAB21 gene family play in organogenesis in mice. It analyzes, at single-cell resolution, the cells that give rise to the retina and lens of the eye.
MembersFaculty
The members of the Veterinary Anatomy Lab consist of faculty, project researchers, collaborative research fellows from agriculture, research support staff, administrative staff, and graduate and undergraduate students.As of 2025
- ProfessorYoshiakira KanaiPublications ↗
- Associate ProfessorHiramatsu RyujiPublications ↗
- Assistant ProfessorAyaka YanagidaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Seminiferous tubule and sperm” Nephron / CC BY-SA 3.0 (cropped)
- Gonad development and sex differentiation: “Seminiferous tubule and sperm low mag” Nephron / CC BY-SA 3.0 (cropped)
- Functions of SOX genes: “Gallbladder - intermed mag” Nephron / CC BY-SA 3.0 (cropped)
- How embryos implant in the uterus: “Mouse blastocyst-microscopy” Enzo
（ポーランド語版ウィキペディアの 投稿者） / CC BY-SA 3.0 (cropped) - Organogenesis and MAB21: “Layers of nerve cells in the retina” National Institutes of Health (NIH) / Public domain (cropped)
- Related lab (Veterinary Reproduction and Breeding Lab): “Cows near Kiel - Maack - July 2010” Smaack / CC BY-SA 4.0 (cropped)
- Related lab (Okada Lab): “Seminiferous tubule and sperm” Nephron / CC BY-SA 3.0 (cropped)
- Related lab (Veterinary Physiology Lab): “Wistar rat” Janet Stephens / Public domain (cropped)
- Related lab (Veterinary Surgery Lab): “Dog in operating room” Anja / CC BY-SA 4.0 (cropped)
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