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Veterinary Surgery Lab
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The lab explores new ways to diagnose and treat cancer in dogs and cats, approaching the problem from both clinical and basic research.
AboutAbout the lab
New diagnostics and treatments that start from clinical questions.
The Veterinary Surgery Lab studies clinically focused topics, centered on tumors (cancer) in dogs and cats.
The lab's activities consist of research and clinical care. Its guiding approach is translational research: problems found in the clinic are investigated through basic research, and the results are then tested in clinical cases.
The lab works on projects such as establishing tumor cell lines and developing CAR-T cell therapy, which uses the power of the immune system to attack cancer.
The lab recruits graduate students, undergraduate students, and researchers regardless of their university or research background, and welcomes lab visits and consultations at any time.
Key terms
- CAR-T cell therapy
- A treatment in which a gene is introduced into T cells, a type of immune cell, so that they can recognize and attack cancer, and the cells are then returned to the body
- Cell line
- Cells that have been made to keep multiplying outside the body. They serve as a research tool for studying things such as how well a drug works
- Translational research
- Research that carries the results of basic research over into the diagnosis and treatment of actual patients (here, dogs and cats)
NewsLab news
A doctoral student won a poster award at the Japanese Society for Patient-Derived Cancer Models
A doctoral student won a poster award at the Japanese Society of Veterinary Oncology
ResearchResearch themes
The lab studies clinically focused topics, centered on tumors in dogs and cats. Its research links basic science and clinical practice, from establishing cell lines as research tools, to analyzing clinical specimens, developing immune-based therapies, and validating them in clinical cases.
*Illustrative imageEstablishing cancer cell lines from dogs and cats
Few tumor cell lines from dogs and cats have been available, which has limited research. The lab has established many cell lines, uses them in its own research, and also shares them with research institutions around the world.
*Illustrative imageAnalyzing cancer specimens in detail
Using next-generation sequencers and inhibitor libraries, the lab searches for the pathology and therapeutic targets of canine and feline tumors. It also works with other universities and companies to develop tests that detect tumors early from blood or urine.
*Illustrative imageImmunity, inflammation, angiogenesis, and cancer
The lab studies the immunity, inflammation, and angiogenesis involved in cancer progression, and develops treatments that target them. It works on approaches such as CAR-T cell therapy, in which genetically modified T cells attack cancer.
*Illustrative imageBringing research results to clinical practice
This is translational research: results from basic research are tested in dogs and cats with cancer, and the findings are fed back into research. Together with a company, the lab has put a genetic test for canine bladder cancer into practical use, and clinical trials of new treatments are also underway.
MembersFaculty
The members of the Veterinary Surgery Lab consist of faculty, professors emeritus, project researchers, academic specialist staff, and doctoral and undergraduate students.As of 2026
- ProfessorTakayuki NakagawaPublications ↗
- Project LecturerKato DaikiPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dog in operating room” Anja / CC BY-SA 4.0 (cropped)
- Establishing cancer cell lines from dogs and cats: “Fluorescence microscopy of the oral cancer cells” Korinna / CC BY 4.0 (cropped)
- Analyzing cancer specimens in detail: “Heatmap” Miguel Andrade at English Wikipedia / Public domain (cropped)
- Immunity, inflammation, angiogenesis, and cancer: “Killer T cells surround a cancer cell” The National Institutes of Health / Public domain (cropped)
- Bringing research results to clinical practice: “Small dog watching a hand-held treat at a veterinary clinic in Newark, New Jersey” Veterinarian Pet Alliance / CC BY 4.0 (cropped)
- Related lab (獣医臨床病理学): “Cat and Dog Cuddling” SeanT313 / CC BY-SA 4.0 (cropped)
- Related lab (感染制御学): “Colorized electron micrograph of HPV virus particles (teal)” NIAID / CC BY 2.0 (cropped)
- Related lab (獣医微生物学研究室): “Colorized transmission electron micrograph of Avian influenza A H5N1 viruses” CDC / Cynthia Goldsmith / Public domain (cropped)
- Related lab (産
業動物臨床学研究室): “Row of Holstein Friesian cows in Bronów” Mikinisk / CC BY-SA 4.0 (cropped)
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