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Cell Genetics Lab
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A lab that investigates, at the molecular level, how the shape of yeast and mold cells and the lipids in their membranes work.

AboutAbout the lab
Research using yeast and filamentous fungi
The Cell Genetics Lab studies eukaryotic microorganisms such as yeast and filamentous fungi (molds).
The lab focuses on how cells form their shapes, and on how compounds such as phospholipids are metabolized and regulated inside cells.
In addition to yeast, a model eukaryote, the lab works with oleaginous yeast, which is attracting attention for industrial use, and with model filamentous fungi.
By clarifying the structures and useful traits that these organisms need for their life activities, the lab aims to advance biotechnology in both basic and applied research.
Key terms
- Eukaryotic microorganisms
- Microorganisms whose cells contain a nucleus. They include yeasts and molds (filamentous fungi).
- Phospholipids
- Lipids that are the main material of the membranes surrounding cells and the organelles inside them.
- n-Alkane
- A hydrocarbon in which carbon atoms are linked in a straight chain. It is one of the components of petroleum.
ResearchResearch themes
The lab clarifies, at the molecular level, the biological phenomena underlying the properties that make yeasts and filamentous fungi useful or harmful. Its research focuses on cell morphogenesis, and on the metabolism and regulation of compounds, including phospholipids, inside cells.
*Illustrative imageHow Membrane Lipids Are Transported
Using the yeast Saccharomyces cerevisiae, the lab studies how membrane lipids such as phospholipids and sterols are delivered to the membranes of organelles such as mitochondria and the endoplasmic reticulum.
*Illustrative imageExchanging Membrane Lipids
Through "remodeling," in which the fatty acid portions of phospholipids are exchanged, cells can adapt to temperature changes and membrane damage. The lab studies the basic mechanism of this process in yeast.
*Illustrative imageGenes of a Yeast That Uses Petroleum Components
The lab studies how the oleaginous yeast Yarrowia lipolytica increases the activity of the genes it needs to utilize n-alkanes and fatty acids in response to them, aiming to apply this to the production of useful substances.
*Illustrative imageYeast Cell Walls and Morphological Changes
In Y. lipolytica, which takes several forms such as a yeast form and a hyphal form, the lab studies the genes involved in building the cell wall and in changes of form, exploring the relationship between form and properties.
MembersFaculty
The members of the Cell Genetics Lab consist of faculty, project researchers, doctoral, master's, and undergraduate students, and research students.As of 2026
- Associate ProfessorRyouichi FukudaPublications ↗
- Assistant ProfessorRyo IwamaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Aspergillus nidulans” Plasmidmap / CC BY 3.0 (cropped)
- How Membrane Lipids Are Transported: “Bakers yeast cytoplasm-nucleus” Tgru001 / CC0 (cropped)
- Exchanging Membrane Lipids: “Lipid Bilayer” US gov / Public domain (cropped)
- Genes of a Yeast That Uses Petroleum Components: “Single cell state of Yarrowia lipolytica” Ger Oliver / CC BY-SA 4.0 (cropped)
- Yeast Cell Walls and Morphological Changes: “Filamentous cell state of Yarrowia lipolytica” Ger Oliver / CC BY-SA 4.0 (cropped)
- Related lab (Microbiology Lab): “Aspergillus oryzae (koji)” Forrest O. / CC BY-SA 2.0 (cropped)
- Related lab (Food Biochemistry Lab): “Bodipy-wiki-Rkott-2023” Rkott / CC BY-SA 4.0 (cropped)
- Related lab (Fermentation Microbiology Lab): “Streptomyces griseus on chocolate agar (Espinoza 2022)” Carlos Espinoza, Pedro Morales, Brenda Perez, Alvaro Hu / CC BY 4.0 (cropped)
- Related lab (Microbial Ecotechnology Social Cooperation Lab): “Разнообразие почвенной микрофлоры в чашке Петри” Oksana Lastochkina / CC BY-SA 4.0 (cropped)
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