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Food Biochemistry Lab
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A lab that explores how foods can help prevent lifestyle-related diseases, starting from the study of lipid metabolism.
AboutAbout the lab
Preventing lifestyle-related diseases through the power of food
The Food Biochemistry Lab focuses on lifestyle-related diseases and studies them from the perspective of regulating lipid metabolism.
Using biochemical methods to investigate life phenomena inside the body, the lab aims to show how the functions of food can be put to use.
Its work ranges from basic research on molecular mechanisms to applied research using human iPS cells and other models.
Through weekly experiment reports and discussion, faculty and students advance research together as one team.
Key terms
- Lipid metabolism
- The processes by which the body makes, breaks down, and transports cholesterol and fats
- Transcription factor
- A protein that binds to DNA and regulates which genes are active and to what extent
- iPS cell
- A cell made from the body's own cells that can develop into many different types of cells
- Organoid
- A small cluster of cells grown from stem cells or similar sources, with a shape and functions resembling those of an organ
NewsLab news
Mechanism by which phycocyanin lowers lipids elucidated using human small intestinal and liver organoids
Cellular senescence model built using human small intestinal organoids
Compound that improves intestinal inflammation identified using human small intestinal organoids
Study reveals which organs the exosomes in blood come from
New factor MCARE, which regulates calcium ions in skeletal muscle, discovered
ResearchResearch themes
The lab studies food science with a view to preventing lifestyle-related diseases and extending healthy life expectancy. It investigates at the molecular level how the body maintains homeostasis and how that balance breaks down, and extends this work to applied research using human iPS cells and other models.
*Illustrative imageTranscription factors that control lipid metabolism
The lab studies the functions of transcription factors such as SREBP, which regulate the amounts of cholesterol and fatty acids in cells. Building on these findings, it also searches for food components that can help improve lipid metabolism.
*Illustrative imageMetabolic mechanisms in skeletal muscle
The lab investigates at the molecular level how metabolism is regulated in skeletal muscle, which plays a role in processes such as blood glucose regulation. With the aim of extending healthy life expectancy, it also studies how muscle is kept in a healthy state.
*Illustrative imageEvaluating food components with human iPS cells
Using human iPS cells and similar models, the lab evaluates the functions of food components and analyzes their mechanisms at the molecular level. It also conducts research using human small intestinal and liver organoids.
*Illustrative imageCommunication between cells and between organs
The lab studies the molecular mechanisms of information exchange within cells, between cells, and between organs. It also works on extracellular vesicles released from tissues.
MembersFaculty
The members of the Food Biochemistry Lab consist of faculty, postdoctoral researchers, corporate researchers, doctoral, master's, and undergraduate students, research students, and administrative assistants, along with faculty affiliated with the Social Cooperation Program.As of 2026
- ProfessorYoshio YamauchiPublications ↗
- Assistant ProfessorYu TakahashiPublications ↗
- Assistant ProfessorTakumi Makino
VoicesStudent voices
Compiled from answers by students who were in the lab. Ratings and reviews reflect individual students' experiences, not the lab's official views.
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Bodipy-wiki-Rkott-2023” Rkott / CC BY-SA 4.0 (cropped)
- Transcription factors that control lipid metabolism: “Liver steatosis fatty change” Laboratory of Experimental Pathology, Division of Intramural Research, NIEHS (NIH) / Public domain (cropped)
- Metabolic mechanisms in skeletal muscle: “Muskel ( 1)” Rollroboter / CC BY-SA 3.0 (cropped)
- Evaluating food components with human iPS cells: “Intestinal organoid” Meritxell Huch / CC BY 4.0 (cropped)
- Communication between cells and between organs: “Human Liver (NIH BioArt 230)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (Food Chemistry Lab (Arai Lab)): “Macrophage ( )” NIAID / CC BY 2.0 (cropped)
- Related lab (Animal Cell Regulation Lab): “Wistar rat” Janet Stephens / Public domain (cropped)
- Related lab (Cell Genetics Lab): “Aspergillus nidulans” Plasmidmap / CC BY 3.0 (cropped)
- Related lab (Analytical Chemistry Lab): “Nacreous aragonite ("mother-of-pearl") 1” James St. John / CC BY 2.0 (cropped)
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