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Suzuki Lab
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A lab that uses next-generation sequencers to decipher how genes function in cancer and infectious diseases.
AboutAbout the lab
Modeling and understanding, powered by next-generation sequencers.
The Suzuki Lab uses next-generation sequencers to read large amounts of genetic data and study diseases and the mechanisms of life.
The lab works on cancer, long-read DNA analysis, spatial transcriptomics (analysis that identifies where genes are active within tissue), and infectious diseases and immunity, among other topics.
The lab also studies gene activity in the bodies of healthy people, with the aim of rethinking the concepts of "health" and "mibyō" (the pre-disease state).
The lab seeks to understand how genetic mutations affect the way genes function, by modeling this through both experiments and computation.
Key terms
- Next-generation sequencer
- A device that can read large numbers of DNA or RNA sequences at once
- Somatic mutation
- A DNA change that occurs in the body's cells after birth. It is not inherited from one's parents
- Promoter
- A region of DNA located just before a gene that determines how strongly that gene is activated
NewsLab news
Published a study capturing the "first moment" of lymph node metastasis in breast cancer
Published the characteristics of the gut microbiome of Japanese people, based on a comparison across 37 countries worldwide
Built VIRE, a database of viruses ranging from humans to oceans and soil
Discovered "Inocle," a giant extrachromosomal element in the human oral cavity (Nature Communications)
Created a new "genome map" of Japanese and Saudi Arabian populations (Scientific Data)
ResearchResearch themes
The lab seeks to understand how genetic mutations affect gene regulation, by modeling it through both the lab's own experiments and computation. Its research centers on cancer genomes, the regulation of gene expression, and the genomes of infectious diseases.
*Illustrative imageCancer Genome Analysis
In collaboration with many hospitals, the lab has investigated somatic mutations that arise in cancer genomes. Using cultured cancer cells as a model, it measures changes in the genome, epigenome, and gene expression in correspondence with one another, and verifies the relationships among them.
*Illustrative imageMeasuring and Modeling Gene Expression Regulation
The lab is developing new technologies to measure each step of gene regulation. It measures, at large scale, the relationship between mutated DNA sequences and promoter activity, and builds predictive models using machine learning.
*Illustrative imageGenome Analysis of Infectious Diseases in the Field
The lab has a field base in Indonesia, where it uses multi-layered omics analysis to study the responses of both the parasite and the human body during infection with malaria parasites.
MembersFaculty
The members of the Suzuki Lab include faculty members, project researchers, academic specialists, project specialists, temporary agency staff, and doctoral and master's students.As of 2026
- ProfessorYutaka SuzukiPublications ↗
- Project ProfessorAkihiro Nakaya
- Project ProfessorFumihito Miura
- Project Associate ProfessorAkinori Kanai
- Project Associate ProfessorSuguru Nishijima
- Project LecturerToshio Shibata
- Project Associate ProfessorMasahide Seki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Illumina HiSeq 2500” Konrad Förstner / CC0 (cropped)
- Cancer Genome Analysis: “Histopathology of poorly differentiated lung adenocarcinoma” Mikael Häggström, M.D. / CC0 (cropped)
- Measuring and Modeling Gene Expression Regulation: “RNA Polymerase II Transcription” Edk006 / CC BY-SA 3.0 (cropped)
- Genome Analysis of Infectious Diseases in the Field: “Plasmodium falciparum (malaria) parasite in blood” MichaelZahniser / Public domain (cropped)
- Related lab (Tsunoda Lab): “IBM Quantum System One” OJB Quantum / CC BY 4.0 (cropped)
- Related lab (Katoh Lab): “Tree of life by Haeckel” Ernst Haeckel / Public domain (cropped)
- Related lab (Kasahara Lab): “MinION portable sequencer” Mongan A.E. / CC BY 4.0 (cropped)
- Related lab (Kuroda Lab): “Insulin Structure” Webridge / CC BY-SA 3.0 (cropped)
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