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Kasahara Lab
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The lab develops analysis technologies that keep pace with new DNA observation technologies.
AboutAbout the lab
New analysis technologies for new observation technologies.
The Kasahara Lab studies technologies for analyzing the massive amounts of data produced by DNA sequencing instruments.
Over the past 20 years or so, the cost of reading DNA has dropped dramatically.
The lab believes that an era of new observation technologies calls for new information analysis technologies that match them.
The lab carries out its research in collaboration with experimental labs whenever possible, and also offers independent research topics for students who prefer them.
Key terms
- Genome assembly
- The process of piecing together the short DNA sequence fragments read by an instrument to reconstruct the sequence of the whole genome
- DNA sequencer
- An instrument that reads the order of bases (the sequence) in DNA. Small, portable models have also begun to appear
- Middleware
- Software that works between basic software and application software to reduce the effort required of its users
ResearchResearch themes
The lab studies information technologies for analyzing data from the new DNA sequencers and single-cell analysis instruments that keep appearing one after another. It develops algorithms and software that connect observation technologies to scientific discoveries in a short amount of time.
*Illustrative imageAnalysis technologies that match new observation technologies
The lab quickly scales up analysis methods for problems such as genome assembly, gene sequence decoding, genome comparison between species and individuals, and inference of functions and causes, so that they can handle very large volumes of data.
*Illustrative imageA private cloud for analysis
Aiming at "high-performance science," which seeks to produce scientific results quickly even if it means using some computing resources wastefully, the lab builds middleware that is convenient for researchers and applies it to the life sciences.
MembersFaculty
- Associate ProfessorMasahiro KasaharaPublications ↗
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RelatedLabs similar to Kasahara Lab
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “MinION portable sequencer” Mongan A.E. / CC BY 4.0 (cropped)
- Analysis technologies that match new observation technologies: “SequelSmrtCell” Owlmonkey / CC BY-SA 4.0 (cropped)
- A private cloud for analysis: “Datacenter Server Racks ( )” Carl Lender from Sunrise, USA / CC BY 2.0 (cropped)
- Related lab (Frith Lab): “DNA double helix 45” Jerome Walker,Dennis Myts / Public domain (cropped)
- Related lab (Kiryu Lab): “RNA structure (2)” Thomas Shafee / CC BY 4.0 (cropped)
- Related lab (Katoh Lab): “Tree of life by Haeckel” Ernst Haeckel / Public domain (cropped)
- Related lab (Tsuda Lab): “Caffeine molecule ball from xtal (1)” Jynto (more from this user) / CC0 (cropped)
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