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遺伝子発現動態学
Showing the original Japanese · View translation
転写バーストのしくみを生きた細胞で追う研究室。
AboutAbout the lab
遺伝子発現の動きを、生きた細胞で見る。
遺伝子発現動態学研究室は、
マウス初期胚、
転写バーストに
老化に
Key terms
- 転写バースト
- 遺伝子から
RNAが 作られる 動きが、 盛んな 活性化状態と ほとんど 止まった 不活性化状態の 間で 切り 替わる 現象 - ライブイメージング
- 生きた
細胞の 中の 分子や 遺伝子の 動きを、 顕微鏡で 時間を 追って 観察する 方法 - 空間オミクス
- 細胞や
組織の 中での 位置を 保ったまま、 遺伝子や 分子の 状態を 網羅的に 調べる 手法
NewsLab news
国立遺伝学研究所との
共同研究が、 Nature Genetics に 掲載 クロマチン修飾と
転写バーストの 連動を 扱う プレプリントを bioRxiv に 公開 RNAイメージングに
よる 転写バーストの 可視化を まとめた 総説が、 月刊 『細胞』に 掲載 遺伝子間の
距離変化に よる 発現調節の 論文が、 Science Advances に 掲載 DNA/RNA/IF-seqFISH の
画像解析プロトコールが、 Methods Mol. Biol. に 公開
ResearchResearch themes
遺伝子の
*Illustrative image転写バーストの制御機構
転写バーストが
*Illustrative image遺伝子発現の多様性と細胞運命
転写バーストに
*Illustrative image老化と細胞間の発現量の違い
老化に
MembersFaculty
遺伝子発現動態学研究室の
- Professor落合 博
- Assistant Professor小林 芳明
- Assistant Professor内野 哲志
- Assistant Professor (Specially Appointed Project Faculty)須摩 美智子
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “TranscriptionGraphic PublicDomain” Zulujive / CC0 (cropped)
- 転写バーストの
制御機構: “Basic diagram of locations of gene expression” NHS National Genetics and Genomics Education Centre / CC BY 2.0 (cropped) - 遺伝子発現の
多様性と 細胞運命: “Single Cell RNA Seq (NIH BioArt 767)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped) - 老化と
細胞間の 発現量の 違い : “The Hallmarks of Aging” Rebelo-Marques, De Sousa Lages, Andrade, Ribeiro, Mota-Pinto, Carrilho and Espregueira-Mendes / CC BY 4.0 (cropped) - Related lab (バイオメディカル情報解析): “Geographical distribution of human major genetic ancestral components” Wikiuser1314 / CC BY-SA 4.0 (cropped)
- Related lab (疾患ゲノム生物学): “Histological section of small intestine epithelial tissue, zoom” Otávio Astor Vaz Costa / CC BY 4.0 (cropped)
- Related lab (トランスクリプトミクス): “Chromatin Structures” Original uploader was Richard Wheeler at en.wikipedia / CC BY-SA 3.0 (cropped)
- Related lab (細胞不均一性学): “Skeletal Muscle Tissue” Community College Bioscience / CC0 (cropped)
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