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Molecular Neuroimmunology Lab
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The lab studies brain physiology and disease through the immune cells inside and at the borders of the brain.
AboutAbout the lab
Exploring brain physiology and disease through immune cells of the brain
The Molecular Neuroimmunology Lab focuses on immune cells found inside the brain and at its borders, and studies brain physiology and disease.
Its research theme is to clarify how brain macrophages, such as microglia and CNS-associated macrophages (CAMs), develop and why they exist.
The faculty's research topics also include understanding brain physiology and disease starting from lipid metabolism, and the role of CNS-associated macrophages in stroke.
On the lab's website, it is introduced under the name "Masuda Lab."
Key terms
- Microglia
- Macrophages that reside permanently in the central nervous system. They are involved in brain development and in the mechanisms of central nervous system diseases.
- CNS-associated macrophages
- Macrophages located at the borders of the brain, such as the meninges and around blood vessels. Abbreviated as CAMs.
ResearchResearch themes
The lab aims to clarify how immune cells inside and at the borders of the brain develop and what roles they play. Focusing on microglia and CNS-associated macrophages (CAMs), it investigates their relationship to brain physiology and disease.
*Illustrative imageDevelopment of brain macrophages
The lab aims to clarify how macrophages in the brain develop and what significance they have. The targets are immune cells of the central nervous system, including microglia and CNS-associated macrophages (CAMs).
*Illustrative imageBrain physiology and disease from the viewpoint of lipid metabolism
The lab aims to understand the mechanisms of physiology and disease in the central nervous system, starting from lipid metabolism.
*Illustrative imageStroke and CNS-associated macrophages
The lab investigates how CNS-associated macrophages (CAMs) behave and adapt to function when a stroke occurs. The research covers the whole process from disease progression to repair.
MembersFaculty
- ProfessorTakahiro Masuda
- Assistant ProfessorShota Yamamoto
- Assistant ProfessorShinichiro Hiraga
- Assistant ProfessorKeisuke Matsubara
- Assistant ProfessorTakahiro Kochi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Fluorescently Labeled Microglia in a Mouse Brain Section” Syed07 / CC BY 4.0 (cropped)
- Development of brain macrophages: “Giemsa Stain Macrophage Illustration” Noah Smith / CC BY-SA 4.0 (cropped)
- Brain physiology and disease from the viewpoint of lipid metabolism: “Fructose impacts metabolism of carbs and lipids” Ravil Niyazov / CC BY-SA 4.0 (cropped)
- Stroke and CNS-associated macrophages: “Lacunar stroke MRI” Ptrump16 / CC BY-SA 4.0 (cropped)
- Related lab (Integrative Omics Lab): “Multichannel pipette-12” real name: Nadina Wiórkiewicz pl.wiki: Nadine90 commons: Nadine90 / CC BY-SA 3.0 (cropped)
- Related lab (Disease Genome Biology Lab): “Histological section of small intestine epithelial tissue, zoom” Otávio Astor Vaz Costa / CC BY 4.0 (cropped)
- Related lab (Cell Heterogeneity Lab): “Skeletal Muscle Tissue” Community College Bioscience / CC0 (cropped)
- Related lab (Gene Expression Dynamics Lab): “TranscriptionGraphic PublicDomain” Zulujive / CC0 (cropped)
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