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免疫ゲノム生物学
Showing the original Japanese · View translation
B細胞の働きから免疫の仕組みと難治疾患に迫る研究室。
AboutAbout the lab
B細胞を軸に難治疾患の原因究明と医学応用を目指す
免疫ゲノム生物学研究室は、
B細胞は
ゲノム、
免疫寛容の
Key terms
- B細胞
- 抗原に
応答して 分化し、 プラズマ細胞は 抗体を 産生する 免疫細胞。 感染防御にも 自己免疫疾患にも 関わる - BCR
- B細胞の
表面に ある 抗原の 受容体。 抗原を 認識し、 その 情報を 細胞内へ 伝える - 免疫寛容
- 自分の
成分に 反応する B細胞が 除去されたり不活化されたりして、 自己免疫疾患が 防がれる 仕組み - 免疫老化
- 加齢に
伴って 免疫機能が 変化し、 感染症の 重症化や ワクチン応答の 低下などが 起こる 現象
NewsLab news
View More ↗ResearchResearch themes
この
*Illustrative imageB細胞が分化する仕組み
B細胞が
*Illustrative image免疫寛容と自己免疫疾患
自分
*Illustrative image加齢と免疫機能の低下
加齢に
*Illustrative imageBCRシグナルとB細胞応答
B細胞が
MembersFaculty
免疫ゲノム生物学研究室の
- Professor馬場 義裕
- Associate Professor田中 伸弥
- Assistant Professor今林 慶祐
- Assistant Professor河田 和彦
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Normal Lymph Node” Ed Uthman, MD / CC BY-SA 2.0 (cropped)
- B細胞が
分化する 仕組み: “Human B Lymphocyte - NIAID” NIAID / CC BY 2.0 (cropped) - 免疫寛容と
自己免疫疾患: “Warm autoimmune hemolytic anemia” E. Uthman, MD / CC BY-SA 2.0 (cropped) - 加齢と
免疫機能の 低下: “Elderly man in Rhodes, Greece (black and white)” Martin Hricko / CC BY 3.0 (cropped) - BCRシグナルと
B細胞応答: “B Cell Receptor (NIH BioArt 617)” Courtesy of NIAID Alexander Stewart / Public domain (cropped) - Related lab (粘膜防御学): “Cell-1” Mk4716 / CC BY-SA 4.0 (cropped)
- Related lab (クロマチン構造機能研究): “Snf2 ATPase domain in complex with a nucleosome” EMBL-EBI / Public domain (cropped)
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