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Sato Lab
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A lab that applies quantum chemistry to whole proteins, aiming at the design of new materials and drugs.

AboutAbout the lab
Calculating whole proteins with quantum chemistry.
Sato Lab studies computational biomolecular science, using computers to calculate large molecules such as proteins.
The lab develops ProteinDF, a program based on density functional theory that calculates all the electrons in a protein.
The lab is carrying out research and development on an integrated simulation system that uses this program.
It aims at applications in industry and society, such as the design of materials and drugs with new functions.
Key terms
- Quantum chemistry
- A field that uses quantum mechanics to investigate the properties of molecules and chemical reactions through calculation
- Density functional theory
- A quantum chemistry method that calculates the states and energies of electrons in a molecule based on electron density
- Molecular orbital
- A description of how electrons are spread out and exist within a molecule
ResearchResearch themes
The lab researches and develops an integrated simulation system built on ProteinDF, an all-electron protein calculation program based on density functional theory. By treating the whole molecular structure of a protein with quantum chemistry, the lab investigates how reactions work and applies the results to areas such as the design of new enzymes and nanomaterials.
*Illustrative imageA computational program for large molecules
The lab develops ProteinDF, a density functional theory program for handling large molecules such as proteins. It can calculate the molecular orbitals of a protein.
*Illustrative imageQCLO: making calculations on large molecules easier
The lab develops QCLO, a program that makes calculations on large molecules easier to carry out, together with ProteinDF.
MembersFaculty
The members of Sato Lab consist of faculty members, academic specialist staff, doctoral and master's students, and technical assistants.
- ProfessorFumitoshi SatoPublications ↗
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “CYP4F2 protein structure” Maxim Masiutin / CC0 (cropped)
- A computational program for large molecules: “Plague Enzyme Structure ( )” National Institute of Standards and Technology / Public domain (cropped)
- QCLO: making calculations on large molecules easier: “Tannic acid ESP” Mplanine / CC BY-SA 4.0 (cropped)
- Related lab (小穴研究室): “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Related lab (大島研究室): “PIV analysis of a stalled flat plate” Willa / CC BY-SA 3.0 (cropped)
- Related lab (梅野研究室): “SEM-image-showing-crack-propagation-of-TaCCNTsSiC” Qiaoyun Xie, Sylvanus N. Wosu / CC BY 4.0 (cropped)
- Related lab (白樫研究室): “Macro view of water droplets on transparent surface” Dreamora96x / CC BY 4.0 (cropped)
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