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Oshima Lab
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The lab uses simulations and experiments to unravel how blood flows, with the aim of achieving predictive medicine.
AboutAbout the lab
Reading blood flow through computation and experiment
The Oshima Lab studies how blood moves through blood vessels (blood flow).
Using medical images taken at hospitals, the lab builds 3D models of blood vessel shapes and simulates each patient's blood flow on computers.
The lab also carries out measurement experiments that make flow visible, using blood vessel models and microscopes.
The lab also conducts research on STEAM education, a way of learning that combines subjects such as science and mathematics.
Key terms
- Medical images
- Images of the inside of the body taken in hospital examinations, such as CT and MRI
- Surrogate model
- A model that learns from the results of time-consuming calculations and quickly gives answers in their place
- Multiscale blood flow analysis
- Blood flow analysis that links separate computational methods to solve for parts of different sizes, from large to small blood vessels
NewsLab news
Announcement: Komaba Research Campus Open House 2026, The University of Tokyo
Announcement: FY2025 graduate school summer admissions (Department of Mechanical Engineering and Graduate School of Interdisciplinary Information Studies)
A master's student received the Young Researcher Excellent Presentation Award at the Biofrontier Lecture Meeting
Komaba Research Campus Open House 2024, The University of Tokyo: the lab also catered to prospective students
Research posters displayed at the graduate school open house of the Department of Mechanical Engineering
ResearchResearch themes
The lab conducts research toward predictive medicine, using blood flow simulations based on medical images and flow measurement experiments with blood vessel models and other setups. The research is divided into three areas: computation, experiments, and STEAM education.
*Illustrative imageQuickly predicting blood flow after surgery
To predict the risk of a complication in which blood flow to the brain suddenly increases after carotid artery surgery (cerebral hyperperfusion), the lab is building neural network surrogate models that can be used in place of simulations.
*Illustrative imageHow drug-carrying particles move toward an aneurysm
Toward a method of treating abdominal aortic aneurysms with micelles, tiny particles that encapsulate a drug, the lab builds models of the vessel wall from pathology images and simulates how the micelles move.
*Illustrative imagePredicting changes in the diameter of abdominal blood vessels
When the celiac artery narrows, the vessels that serve as detours gradually become thicker. The lab develops numerical analysis methods to predict this change (vascular remodeling) and investigates how blood reaches the internal organs.
*Illustrative imageBlood flow analysis linking the whole body and the brain
The lab is developing multiscale blood flow analysis methods that represent systemic blood circulation with simple 1D and 0D models and link the results to 3D blood flow analysis of the carotid arteries and other vessels.
MembersFaculty
The members of the Oshima Lab consist of faculty members, doctoral and master's students, researchers, and support staff.As of 2026
- ProfessorMarie OshimaPublications ↗
- Project Assistant ProfessorYan CHENPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “PIV analysis of a stalled flat plate” Willa / CC BY-SA 3.0 (cropped)
- Quickly predicting blood flow after surgery: “Circle of Willis - MRI, MIP - Superior view” Ceccomaster / CC BY-SA 3.0 (cropped)
- How drug-carrying particles move toward an aneurysm: “Angioscanner 3D AAA” Haudebourg / CC BY-SA 3.0 (cropped)
- Predicting changes in the diameter of abdominal blood vessels: “Image04-MRay01” I own the company that made this work（https://www.scientificanimations.com/） / CC BY-SA 4.0 (cropped)
- Blood flow analysis linking the whole body and the brain: “Inkompletter Circulus willisii - TOF” Hellerhoff / CC BY-SA 3.0 (cropped)
- Related lab (原田研究室
（医療材料・機器工学） ): “WBAMC first in DoD to use robot for surgery 160426-A-EK666-526” Marcy Sanchez / Public domain (cropped) - Related lab (伊藤裕介研究室): “Femtosecond Laser and Pulse Compressor - Optics Lab - INRIM” Giorgio Brida from Torino, Italy / CC BY 2.0 (cropped)
- Related lab (小穴研究室): “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Related lab (梅野研究室): “SEM-image-showing-crack-propagation-of-TaCCNTsSiC” Qiaoyun Xie, Sylvanus N. Wosu / CC BY 4.0 (cropped)
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